Difluoromethyl phenyl sulfone

CHF 102.00
In stock
CDX-D0401-GG252.5 gCHF 102.00
CDX-D0401-G01010 gCHF 299.00
More Information
Product Details
Synonyms Phenyl difluoromethyl sulfone
Product Type Chemical
Formula C7H6F2O2S
MW 192.2
CAS 1535-65-5
Source/Host Chemicals Synthetic.
Purity Chemicals ≥98% (HPLC)
Appearance Colorless to light yellow semi-solid or solid.
Solubility Soluble in chloroform.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Smiles FC(F)S(=O)(=O)C1=CC=CC=C1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Building block for synthesis. Has been used for nucleophilic difluoro(phenylsulfonyl)methylation of carbonyls, reductive silylation and the preparation of trifluoro- and difluoromethylsilanes, fluoroalkylation/chloroalkylation of α,β-enones, arynes, acetylenic ketones and other Michael acceptors and difluoromethylation of primary alkyl halides . It is also used in preparation of α-difluoromethyl amines, anti-difluoropropanediols, β-difluoromethylated and β-difluoromethylenated alcohols and amines, difluoroalkenes, difluoromethyl alcohol derivatives and fluoromethylated vicinal ethylenediamines.

Product References

(1) G.K.S. Prakash, et al.; J. Org. Chem. 68, 4457 (2003) | (2) G.K.S. Prakash, et al.; Angew. Chem. 42, 5216 (2003) | (3) G.K.S. Prakash, et al.; Angew. Chem. 43, 5203 (2004) | (4) G.K.S. Prakash, et al.; Org. Lett. 6, 4315 (2004) | (5) Y. Li & J. Hu; Angew. Chem. 44, 5882 (2005) | (6) G.K.S. Prakash, et al.; Europ. J. Org. Chem. 11, 2218 (2005) | (7) C. Ni, et al.; Angew. Chem. 46, 786 (2007) | (8) J. Liu, et al.; J. Org. Chem. 72, 3119 (2007) | (9) C. Ni, et al.; J. Org. Chem. 73, 5699 (2008) | (10) M. Hu, et al.; J. Fluor. Chem. 155, 52 (2013)

© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.