Chemodex

1,1'-Dimethyl-3,3,3',3'-tetramethyl indocarbocyanine iodide

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Product Details
Synonyms DiIC1(3); HICI; NK 79; 1,1',3,3,3',3'-Hexamethylindocarbocyanine iodide; Cy3 dimethyl;
Product Type Chemical
Properties
Formula C25H29N2 . I
MW 484.43
CAS 25470-94-4
Source/Host Chemicals Synthetic
Purity Chemicals ≥98% (HPLC)
Appearance Dark purple solid.
Solubility Soluble in DMSO.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturer's product datasheet.

InChi Key ZGBJQZCIUVDAHE-UHFFFAOYSA-M
Smiles CN1C=2C(C(C)(C)C1=CC=CC=3C(C)(C)C=4C([N+]3C)=CC=CC4)=CC=CC2.[I-]
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep under inert gas.
Protect from light and oxygen.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
Product Specification Sheet
Datasheet Download PDF
Description
DiIC1(3) is a fluorescent carbocyanine dye used mainly for assessing membrane potential in mitochondria and plasma membranes, especially in flow cytometry and fluorescence microscopy. DiIC1(3) has short alkyl chains (methyl groups), so it diffuses more easily but is less stably anchored in membranes than longer-chain versions like DiIC12(3) or DiIC18(3). It is ideal for dynamic membrane potential assessments, not long-term labeling. The dye can be used as a non-reactive fluorophore, for control experiments and for calibration. Spectral Data: Excitation max: ~ 555nm, Emission max: ~570nm (accord. Lit).
Product References
(1) P.M.W. French & J.R. Taylor; Opt. Lett. 11, 297 (1986) | (2) H. Sato, et al.; J. Raman Spectr. 19, 129 (1988) | (3) A.S. Tatikolov, et al.; Chem. Phys. Lett. 190, 291 (1992) | (4) Z.-H. Peng, et al.; J. Mater. Chem. 6, 559 (1996) | (5) A.L. Mikheikin, et al.; J. Biomol. Struct. Dyn. 18, 59 (2000) | (6) H.M. Shapiro; Cytometry 43, 223 (2001) | (7) M. Matsui, et al.; Tetrahedr. 71, 3528 (2015)
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