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Chemodex
7-(Diethylamino)-3-(4-isothiocyanatophenyl)-4-methylchromen-2-one
271
CHF
CHF 271.00
In stock
CDX-D1035-M02525 mgCHF 271.00
CDX-D1035-M05050 mgCHF 451.00
| Product Details | |
|---|---|
| Synonyms | 7-diethylamino-3-(4'-isothiocyanatophenyl)-4-methylcoumarin; CPI |
| Product Type | Chemical |
| Properties | |
| Formula | C21H20N2O2S |
| MW | 364.46 |
| CAS | 107743-39-5 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥97% (NMR) |
| Appearance | Light yellow powder or chunks. |
| Solubility | Soluble in DMSO. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | YALJZNKPECPZAS-UHFFFAOYSA-N |
| Smiles | CCN(CC)C1=CC2=C(C=C1)C(C)=C(C(=O)O2)C1=CC=C(C=C1)N=C=S |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
7-Diethylamino-3-(4'-isothiocyanatophenyl)-4-methylcoumarin (CPI) is a fluorescent labeling reagent that reacts covalently with amino groups. It is a isothiocyanate derivative of coumarin. It has a high quantum yield (0.75-0.78), long wavelength excitation, and high stability, which makes it ideally suited as fluorescent label for proteins. The quantum yield is little affected by the pH of solutions. Spectral Data: λem = 396nm; λem = 478nm.
Product References
(1) T. Hiratsuka; J. Biochem. 101, 1457 (1987) | (2) L. Erijman & G. Weber; Photoch. Photobiol. 57, 411 (1993) | (3) A. Buchynskyy, et al.; Eur. J. Org. Chem. 2002, 1149 (2002)