Chemodex

7-(Diethylamino)-3-(4-isothiocyanatophenyl)-4-methylchromen-2-one

CHF 271.00
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CDX-D1035-M02525 mgCHF 271.00
CDX-D1035-M05050 mgCHF 451.00
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Product Details
Synonyms 7-diethylamino-3-(4'-isothiocyanatophenyl)-4-methylcoumarin; CPI
Product Type Chemical
Properties
Formula C21H20N2O2S
MW 364.46
CAS 107743-39-5
Source/Host Chemicals Synthetic
Purity Chemicals ≥97% (NMR)
Appearance Light yellow powder or chunks.
Solubility Soluble in DMSO.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key YALJZNKPECPZAS-UHFFFAOYSA-N
Smiles CCN(CC)C1=CC2=C(C=C1)C(C)=C(C(=O)O2)C1=CC=C(C=C1)N=C=S
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
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Product Specification Sheet
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Description

7-Diethylamino-3-(4'-isothiocyanatophenyl)-4-methylcoumarin (CPI) is a fluorescent labeling reagent that reacts covalently with amino groups. It is a isothiocyanate derivative of coumarin. It has a high quantum yield (0.75-0.78), long wavelength excitation, and high stability, which makes it ideally suited as fluorescent label for proteins. The quantum yield is little affected by the pH of solutions. Spectral Data: λem = 396nm; λem = 478nm.

Product References

(1) T. Hiratsuka; J. Biochem. 101, 1457 (1987) | (2) L. Erijman & G. Weber; Photoch. Photobiol. 57, 411 (1993) | (3) A. Buchynskyy, et al.; Eur. J. Org. Chem. 2002, 1149 (2002)

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