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MQAE
268
CHF
CHF 268.00
In stock
CDX-E0001-M200200 mgCHF 268.00
CDX-E0001-G0011 gCHF 1'046.00
| Product Details | |
|---|---|
| Synonyms | 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide |
| Product Type | Chemical |
| Properties | |
| Formula | C14H16NO3Br |
| MW | 326.19 |
| CAS | 162558-52-3 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥97% (TLC) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in water, methanol or DMSO. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | DSLLHVISNOIYHR-UHFFFAOYSA-M |
| Smiles | [Br-].CCOC(=O)C[N+]1=CC=CC2=CC(OC)=CC=C12 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
MQAE is a fluorescent chloride ion indicator for chloride measurement in cells. MQAE is a fluorescent indicator that is quenched via collision with chloride. The probe is suitable for detection of chloride concentrations in liposomes, reconstituted membranes or in extracellular medium. As a UV-excitable indicator, it can be detected using an argon-ion laser for confocal microscopy and flow cytometry applications. MQAE has greater sensitivity than SPQ and higher fluorescence quantum yield. Spectral Data: λex 350nm; λem 460nm in 0.1 M borate pH 8.0 (quenching with Cl-).
Product References
(1) A.S. Verkman, et al.; Anal. Biochem. 178, 355 (1989) | (2) A.S. Verkman; Am. J. Physiol. 259, C375 (1990) | (3) C. Koncz, et al.; Am. J. Physiol. 267, H2114 (1994) | (4) C. Andersson, et al.; Microscopy Res. Tech. 59, 531 (2002) | (5) Z.F. Lai, et al.; Eur. J. Pharmacol. 482, 1 (2003) | (6) F. Munkonge, et al.; J. Cyst. Fibros. 3 Suppl. 2, 171 (2004) | (7) H. Miyazaka, et al.; Am. J. Phys. 292, F1411 (2007) | (8) R.W. Sabnis; Handbook of biological dyes and stains (2010) | (9) Y. Kovalchuk, et al.; Cold Spring Harb Protoc. 2012, 778 (2012)
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