CHF 162.00
In stock
CDX-E0090-M05050 mgCHF 162.00
CDX-E0090-M250250 mgCHF 489.00
More Information
Product Details
Synonyms EAL; Enalapril acid; MK-422
Product Type Chemical
Formula C18H24N2O5
MW 348.4
CAS 76420-72-9
RTECS TW3590600
Source/Host Chemicals Synthetic.
Purity Chemicals ≥99% (HPLC)
Appearance White solid.
Solubility Slightly soluble in water.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Smiles C[C@H](N[C@@H](CCC1=CC=CC=C1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Active metabolite enalapril. Nonsulfhydryl angiotensin-converting enzyme (ACE) inhibitor. Shown to improve cardiac preservation via bradykinin receptor and PKC without affecting ATP metabolism. Has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway. Increases PPARβ/δ expression, without influence on PPARα and PPARγ.

Product References

(1) D.J. DiPette, et al.; Clin. Pharmacol. Ther. 38, 199 (1985) | (2) J.G. Kelly & K. O'Malley; Clin. Pharmacokinet. 19, 177 (1990) | (3) X. Yang, et al.; J. Mol. Cell Cardiol. 28, 1445 (1996) | (4) R. Lupi, et al.; Eur. J. Endocrinol. 154, 355 (2006) | (5) M. Yu, et al.; Molecules 17, 2738 (2012) | (6) H. Cernecka, et al.; Eur. J. Pharmacol. 714, 472 (2013)

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