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Chemodex
Ellagic acid
Product Details | |
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Synonyms | 4,4',5,5',6,6'-Hexahydroxydiphenic acid 2,6,2',6'-dilactone; Alizarin Yellow; Benzoaric acid; Elagostasine; Gallogen; Lagistase; TBBD |
Product Type | Chemical |
Properties | |
Formula |
C14H6O8 |
MW | 302.19 |
CAS | 476-66-4 |
RTECS | DJ2620000 |
Source/Host Chemicals | Plant |
Purity Chemicals | ≥95% (HPLC) |
Appearance | Brown powder. |
Solubility | Slightly soluble in ethanol or DMSO (<1mg/ml). |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | AFSDNFLWKVMVRB-UHFFFAOYSA-N |
Smiles | OC1=CC2=C3C(OC(C4=C3C(OC2=O)=C(O)C(O)=C4)=O)=C1O |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
Ellagic acid is a polyphenolic antioxidant that is abundant in many fruits, vegetables, plant bark and peels. It has antioxidant, anticancer, neuroprotective, antimutagenic, anti-inflammatory and organ-preserving properties. It alters cytochrome P450 activity and improvea metabolism and clearance of xenobiotics, as well as altera immune function. Selective, ATP-competitive inhibitor of casein kinase 2 (CK2). Ellagic acid also blocks methylation of arginine 17 of histone 3 (H3R17) by coactivator-associated arginine methyltransferase 1 (CARM1) without significantly altering histone acetylase or DNA methyltransferase activity. It acts as a scavenger of oxygen species produced by hydrogen peroxide treatment and as a protector of the DNA double helix from alkylating agent injury. Also reported to inhibit topoisomerases I and II and gyrase and glutathione S-transferase.
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