Folic acid

CHF 57.00
In stock
CDX-F0230-G02525 gCHF 57.00
CDX-F0230-G100100 gCHF 185.00
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Product Details
Synonyms Vitamin Bc; Vitamin Be; Vitamin B9; NSC 3073; PteGlu; Pteroyl-L-glutamic acid; Pteroylglutamic acid; Vitamin M; N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid; Pteroylmonoglutamic acid
Product Type Chemical
Properties
Formula C19H19N7O6
MW 441.40
CAS 59-30-3
Purity Chemicals ≥95% (HPLC)
Appearance Yellow to orange crystalline powder.
Solubility Soluble in 1M NaOH (50 mg/ml), diluted acids or allkaline solutions. Slightly soluble in water (1.6mg/ml) or methanol.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key OVBPIULPVIDEAO-LBPRGKRZSA-N
Smiles O=C(O)[C@](NC(C1=CC=C(NCC2=NC3=C(N=C2)N=C(N)NC3=O)C=C1)=O)([H])CCC(O)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +4°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Folic acid, also known as folate, is a B vitamin is an essential nutritional component of the human diet. It is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis, and for preventing changes to DNA, and consequently cancer. It is especially important during periods of frequent cell division and growth, such as infancy and pregnancy. Folate is needed to carry one-carbon groups for methylation reactions and nucleic acid synthesis. Folic acid deficiency hinders DNA synthesis and cell division, affecting hematopoietic cells and neoplasms the most because of their greater frequency of cell division. Both adults and children need folate to make normal red and white blood cells and prevent anemia. Deficiency of folic acid in pregnant women has been implicated in neural tube defects (NTD).

Product References

(1) B. Kamen; Semin. Oncol. 24, S18-30 (1997) | (2) Y.I. Kim; Nutr. Rev. 57, 314 (1999) | (3) S.W. Choi & J.B. Mason; J. Nutr. 130, 129 (2000) | (4) P. Mastroiacovo & E. Leoncini; Biofactors 37, 272 (2011) | (5) S.Y. Taylor, et al.; Eur. J. Pharmacol. 714, 193 (2013) | (6) N. Laurieri, et al.; PLoS One 9, e96370 (2014) | (7) S.Y. Hwang, et al.; Int. J. Mol. Med. 36, 1073 (2015) | (8) H.N. Moussa, et al.; Future Sci. OA. 2, 2 (2016)

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