L-Glutathione reduced

CHF 43.00
In stock
CDX-G0005-G0055 gCHF 43.00
CDX-G0005-G02525 gCHF 118.00
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Product Details
Synonyms GSH; L-γ-glutamyl-L-cysteinyl-glycine
Product Type Chemical
Properties
Formula C10H17N3O6S
MW 307.32
CAS 70-18-8
Purity Chemicals ≥98% (Titration)
Appearance White crystalline powder.
Solubility Soluble in water (20 mg/ml) or PBS (10mg/ml). Sparingly soluble in DMSO or ethanol.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key RWSXRVCMGQZWBV-WDSKDSINSA-N
Smiles OC([C@H](CCC(N[C@@H](CS)C(NCC(O)=O)=O)=O)N)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
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Product Specification Sheet
Datasheet Download PDF

Major tripeptide widely distributed in both plants and animals. Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Regulates activity of the redox sensitive transcription factor NF-κB. Cytoprotective. Serves as a nucleophilic co-substrate to glutathione transferases in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. Involved in amino acid transport and maintenance of protein sulfhydryl reduction status. Posseses several metabolic, regulatory and protective functions. Forms disulfide bonds with cysteine residues in proteins.

Product References

(1) A. Pompella, et al.; Biochem. Pharmacol. 66, 1499 (2003) | (2) A. Pastore, et al.; Clin. Chim. Acta. 333, 19 (2003) | (3) A. Chatterjee; Nutrients 5, 525 (2013) | (4) E.V. Kalinina, et al.; Biochemistry 79, 1562 (2014) | (5) K. Aquilano, et al.; Front. Pharmacol. 5, 196 (2014) | (6) P. Diaz-Vivancos, et al.; Free Radic. Biol. Med. 89, 1154 (2015) | (7) T. Homma & J. Fujii; Curr. Drug Metab. 16, 560 (2015)

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