Guanosine

CHF 45.00
In stock
CDX-G0035-G0055 gCHF 45.00
CDX-G0035-G05050 gCHF 83.00
CDX-G0035-G100100 gCHF 140.00
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Product Details
Synonyms 9-β-D-Ribofuranosyl-guanine; Guanine-9-β-D-ribofuranoside; 2-Amino-β-D-ribofuranosyl-9H-purine-6-(1H)-one
Product Type Chemical
Properties
Formula C10H13N5O5
MW 283.24
CAS 118-00-3
Purity Chemicals ≥98% (HPLC)
Appearance White to light yellow powder.
Solubility Soluble in formic acid:water (1:1) (~50mg/ml).
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key NYHBQMYGNKIUIF-UUOKFMHZSA-N
Smiles O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1CO
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP) and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction and intracellular signal transduction (cGMP). Guanosine has important functions in cell metabolism and a protective role in response to degenerative diseases or injury with neurotrophic and neuroprotective effects. Required for an RNA splicing reaction in mRNA, when a "self-splicing" intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein.

Product References

(1) M. Rathbone, et al.; Nucleosides Nucleotides Nucleic Acids 27, 666 (2008) | (2) D. Lanznaster, et al.; Aging Dis. 7, 657 (2016)

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