GABA

CHF 51.00
In stock
CDX-G0043-G0055 gCHF 51.00
CDX-G0043-G05050 gCHF 83.00
CDX-G0043-G500500 gCHF 166.00
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Product Details
Synonyms 4-Aminobutanoic acid; Piperidic acid; Piperidinic acid; γ-Aminobutyric acid
Product Type Chemical
Properties
Formula C4H9NO2
MW 103.12
CAS 56-12-2
Purity Chemicals ≥99% (Titration)
Appearance White crystals or crystalline powder.
Solubility Soluble in water.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key BTCSSZJGUNDROE-UHFFFAOYSA-N
Smiles OC(CCCN)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +20°C.
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Product Specification Sheet
Datasheet Download PDF

An amino acid that functions as the major inhibitory neurotransmitter in the mammalian central nervous system and also functions as a neuromodulator in some peripheral tissues. GABAA and GABAB receptor agonist that increases Cl− conductance. GABA acts at inhibitory synapses in the brain by binding to specific transmembrane receptors in the plasma membrane of both pre- and postsynaptic neuronal processes. This binding causes the opening of ion channels to allow the flow of either negatively charged chloride ions into the cell or positively charged potassium ions out of the cell. This action results in a negative change in the transmembrane potential, usually causing hyperpolarization. GABAergic neurons are involved in myorelaxation, anxiolytic treatment, sedation and anaesthetics. GABA can also influence heart rate and blood pressure and function as a immunomodulator.

Product References

(1) H.A. Al-Wadei, et al.; Mol. Nutr. Food Res. 55, 1745 (2011) | (2) Z. Jin, et al.; Amino Acids 45, 87 (2013) | (3) C.A. Huebner & K. Holthoff; Front. Cell Neurosci. 7, 177 (2013) | (4) T. Crowley, et al.; Brain Behav. Immun. 54, 260 (2016) | (5) N.X. Tritsch, et al.; Nat. Rev. Neurosci. 17, 139 (2016) | (6) R. Mazzoli & E. Pessione; Front. Microbiol. 7, 1934 (2016)

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