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Chemodex
Gentamicin sulfate
As low as
271
CHF
CHF 271.00
In stock
Only %1 left
CDX-G0050-G01010 gCHF 271.00
CDX-G0050-G05050 gCHF 812.00
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| Product Details | |
|---|---|
| Synonyms | Apogen; Garamycin; Gentiomycin C; Refobacin; NSC-82261 |
| Product Type | Chemical |
| Properties | |
| Formula | n/a |
| MW | n/a |
| CAS | 1405-41-0 |
| Source/Host Chemicals | Microbial |
| Appearance | White to off-white powder. |
| Solubility | Soluble in water (50 mg/ml). |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | RDEIXVOBVLKYNT-HDZPSJEVSA-N |
| Smiles | O=S(O)(O)=O.O[C@]1(C)[C@@H]([C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@@](CC[C@H]3N)([C@@H](C)NC)[H])[C@@H](N)C[C@H]2N)OC1)NC.O[C@]4(C)[C@@H]([C@@H](O)[C@@H](O[C@@H]5[C@@H](O)[C@H](O[C@H]6O[C@@](CC[C@H]6N)([C@@H](C)N)[H])[C@@H](N)C[C@H]5N)OC4)NC.O[ |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice |
Keep under inert gas. Protect from light and oxygen. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Gentamicin sulfate is a broad-spectrum aminoglycoside antibiotic used to treat a wide range of bacterial infections. It is antibacterial against Gram-negative aerobic bacteria, Gram-positive bacteria and mycoplasmas. Gentamicin sulfate is a protein synthesis inhibitor. It causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site. Gentamicin sulfate is used as a selection agent (gentamicin-resistance gene) in molecular biology applications. It is a broad-spectrum cell culture antibiotic that is nontoxic to viruses and mammalian cells at antibacterial and antimycoplasmal concentrations. Due to its extended stability and slow development of bacterial resistance, it is a useful antibiotic in long-term virus und tissue culture studies.
Product References
(1) M. Finland; Med. Times 97, 161 (1969) (Review) | (2) R.E. Hancock; J. Antimicrob. Chemother. 8, 249 (1981) (Review) | (3) E. Hancock; J. Antimicrob. Chemother. 8, 429 (1981) (Review) | (4) N.L. Martin & T.J. Beveridge; Antimicrob. Agents Chemother. 29, 1079 (1986) | (5) J.P. Montenez, et al.; Toxicol. Lett. 73, 201 (1994) | (6) F.C. Luft; J. Mol. Med. 80, 543 (2002) (Review) | (7) Y. Quiros, et al.; Toxicol. Sci. 119, 245 (2011) (Review)