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Chemodex
Galangin
Product Details | |
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Synonyms | 3,5,7-Trihydroxyflavone; Norizalpinin; NSC 407229 |
Product Type | Chemical |
Properties | |
Formula |
C15H10O5 |
MW | 270.24 |
CAS | 548-83-4 |
RTECS | LK9275500 |
Source/Host Chemicals | Plant |
Purity Chemicals | ≥98% (HPLC) |
Appearance | Light yellow powder. |
Solubility | Soluble in DMSO (20mg/ml), DMF (20mg/ml) or ethanol (10mg/ml). |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | VCCRNZQBSJXYJD-UHFFFAOYSA-N |
Smiles | OC1=C2C(OC(C3=CC=CC=C3)=C(O)C2=O)=CC(O)=C1 |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
Galangin is a flavonoid naturally found in herbs used in traditional medicine. It has diverse biological activities, including potent antioxidant, anti-inflammatory, antiobesity, antidiabetic, anti-cancer, neuroprotective, antiviral and antibacterial properties. Galangin has anti-inflammatory actions related to suppression of signaling through NF-κ/NRLP3 pathway. Galangin induces apoptosis and autophagy in different cancer cells. It is a TRPC5 inhibitor, inhibiting Ca2+ entry into TRPC5 expressing cells. Galangin as a potential DPP-4 inhibitor that improves insulin-stimulated skeletal muscle glucose uptake.
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