Chemodex

5,7-Dihydroxytryptamine hydrobromide

CHF 204.00
In stock
CDX-H0026-M01010 mgCHF 204.00
CDX-H0026-M02525 mgCHF 407.00
CDX-H0026-M250250 mgCHF 3'256.00
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Product Details
Synonyms 5,7-DHT; 3-(2-Aminoethyl)-1H-indole-5,7-diol
Product Type Chemical
Properties
Formula C10H12N2O2 . HBr
MW 192.2 . 80.9
CAS 31363-74-3 (free base)
Source/Host Chemicals Synthetic
Purity Chemicals ≥95% (HPLC)
Appearance Grey-brown powder.
Solubility Soluble in water.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key KVRZGCBQKAJSBN-UHFFFAOYSA-N
Smiles [Br-].[NH3+]CCC1=CNC2=C(O)C=C(O)C=C12
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

Autofluorescent serotonin derivative. Serotonergic neurotoxin, depleting serotonin and norepinephrine. Can be used for the identification of living serotonergic neurons even in the presence of dopaminergic neurons. Its selectively uptaken into 5-hydroxytryptamine neurons. It’s oxidation products are often more potent then the parent product.

Product References

(1) H.G. Baumgarten, et al.; Acta Physiol. Scand. Suppl. 391, 1 (1973) | (2) B. Allis & G. Cohen; Eur. J. Pharmacol. 43, 269 (1977) | (3) K. Fuxe, et al.; Ann. N. Y. Acad. Sci. 305, 346 (1978) | (4) M.Z. Wrona, et al.; J. Med. Chem. 29, 499 (1986) | (5) A.K. Sinhababu & R.T. Borchardt; Neurochem. Int. 12, 273 (1988) | (6) K.T. Finnegan, et al.; Brain. Res. 496, 251 (1989) | (7) H. Franke,et al.; Naunyn Schmiedebergs Arch. Pharmacol. 366, 315 (2002)

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