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Chemodex
5,7-Dihydroxytryptamine hydrobromide
Product Details | |
---|---|
Synonyms | 5,7-DHT; 3-(2-Aminoethyl)-1H-indole-5,7-diol |
Product Type | Chemical |
Properties | |
Formula | C10H12N2O2 . HBr |
MW | 192.2 . 80.9 |
CAS | 31363-74-3 (free base) |
Source/Host Chemicals | Synthetic |
Purity Chemicals | ≥95% (HPLC) |
Appearance | Grey-brown powder. |
Solubility | Soluble in water. |
Identity | Determined by NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | KVRZGCBQKAJSBN-UHFFFAOYSA-N |
Smiles | [Br-].[NH3+]CCC1=CNC2=C(O)C=C(O)C=C12 |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice |
Keep cool and dry. Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Autofluorescent serotonin derivative. Serotonergic neurotoxin, depleting serotonin and norepinephrine. Can be used for the identification of living serotonergic neurons even in the presence of dopaminergic neurons. Its selectively uptaken into 5-hydroxytryptamine neurons. It’s oxidation products are often more potent then the parent product.
(1) H.G. Baumgarten, et al.; Acta Physiol. Scand. Suppl. 391, 1 (1973) | (2) B. Allis & G. Cohen; Eur. J. Pharmacol. 43, 269 (1977) | (3) K. Fuxe, et al.; Ann. N. Y. Acad. Sci. 305, 346 (1978) | (4) M.Z. Wrona, et al.; J. Med. Chem. 29, 499 (1986) | (5) A.K. Sinhababu & R.T. Borchardt; Neurochem. Int. 12, 273 (1988) | (6) K.T. Finnegan, et al.; Brain. Res. 496, 251 (1989) | (7) H. Franke,et al.; Naunyn Schmiedebergs Arch. Pharmacol. 366, 315 (2002)