3-cis-Hydroxyglibenclamide

CHF 147.00
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CDX-H0030-M0011 mgCHF 147.00
CDX-H0030-M0055 mgCHF 587.00
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Product Details
Synonyms 3-cis-Hydroxycyclohexyl glyburide; cis-3-Hydroxyglyburide
Product Type Chemical
Properties
Formula C23H28ClN3O6S
MW 510.0
CAS 23074-02-4
Source/Host Chemicals Synthetic.
Purity Chemicals ≥97% (HPLC)
Appearance White to off-white powder.
Solubility Sligthly soluble in DMSO or methanol.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key VFBAJFAMXTVSQA-ZWKOTPCHSA-N
Smiles COC1=C(C(NCCC2=CC=C(S(=O)(NC(N[C@H]3CCC[C@@H](O)C3)=O)=O)C=C2)=O)C=C(Cl)C=C1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
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Product Specification Sheet
Datasheet Download PDF

M2-Metabolite of the antidiabetic compound glyburide. Antidiabetic reagent. Shows 50% hypoglycaemic activity of the parent compound, by increasing insulin secretion. Compound can be used as analytical reference material.

Product References

(1) W. Heptner, et al.; Pharmaceut. Res. 5, 215 (1984) | (2) T. Rydberg, et al.; J. Chromatogr. 564, 223 (1991) | (3) T. Rydberg, et al.; Diabetes Care 17, 1026 (1994) | (4) T. Rydberg, et al.; J. Clin. Pharm. Ther. 20, 283 (1995) | (5) T. Rydberg, et al.; Br. J. Clin. Pharm. 43, 373 (1997)

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