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Chemodex
Hyperoside
272
CHF
CHF 272.00
In stock
CDX-H0298-M02525 mgCHF 272.00
| Product Details | |
|---|---|
| Synonyms | 3,3',4',5,7-Pentahydroxyflavone 3-D-galactoside; Hyperin; Quercetin 3-D-galactoside; NSC 407304 |
| Product Type | Chemical |
| Properties | |
| Formula |
C21H20O12 |
| MW | 464.38 |
| CAS | 482-36-0 |
| RTECS | DJ3009200 |
| Source/Host Chemicals | Plant |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Yellow powder. |
| Solubility | Soluble in DMSO (10mg/ml) or DMF (10mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | OVSQVDMCBVZWGM-DTGCRPNFSA-N |
| Smiles | O=C1C2=C(O)C=C(O)C=C2OC(C3=CC=C(O)C(O)=C3)=C1O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O)[C@H]4O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Hyperoside is a 3-O-galactoside of quercetin that can be found in a wide range of plants. It shows diverse biological activities, including antioxidant, anti-inflammatory, neuroprotective, antihypoglycemic and antiadipogenic, antibacterial and anticancer properties. It has powerful antioxidant action through its ability to scavenge free radicals. It inhibits the NF-κB signaling pathway. Hyperoside selectively interrupted NLRC4 and AIM2 inflammasome activation but did not alter cytokine expression. The quorum sensing-inhibiting effect of hyperoside may lead to a reduction in biofilm formation in P. aeruginosa. Honokiol exerts broad-range anticancer activity, such as induction of apoptosis and autophagy and inhibition of cell proliferation. Hyperoside has a beneficial effect on the prevention and treatment of obesity.
Product References
(1) M.J. Piao, et al.; Biochim. Biophys. Acta 1780, 1448 (2008) | (2) S.J. Kim, et al.; Am. J. Chin. Med. 39, 171 (2011) | (3) K.W. Zeng, et al.; Eur. J. Pharmacol. 672, 45 (2011) | (4) N. Zhang, et al.; PLoS One 9, e98973 (2014) | (5) S.K. Ku, et al.; Inflammation 38, 784 (2015) | (6) T. Fu, et al.; Acta Pharmacol. Sin. 37, 505 (2016) | (7) P. Lu; Biomed. Pharmacother. 82, 216 (2016) | (8) H. Ahn & G.S. Lee; Phytomedicine 24, 77 (2017) | (9) Y. Sun, et al.; Exp. Ther. Med. 14, 1647 (2017) | (10) Y. Zhang, et al.; Int. J. Mol. Med. 41, 77 (2018) | (11) M. Berkoz; Acta Endocrinol. 15, 165 (2019)