Ibuprofen Impurity K

Specifications / Handling

More Information
Product Details
Synonyms	(2RS)-2-(4-Formylphenyl)propionic acid; FPP
Product Type	Chemical
Properties
Formula	C₁₀H₁₀O₃
MW	178.18
CAS	43153-07-7
Source/Host Chemicals	Synthetic
Purity Chemicals	≥98% (HPLC)
Appearance	White to off-white powder or crystals.
Solubility	Soluble in DMSO or methanol (1mg/ml).
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	IAXYHYOWEQQFMC-UHFFFAOYSA-N
Smiles	OC(C(C)C1=CC=C(C([H])=O)C=C1)=O
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

The metabolite (2RS)-2-(4-Formylphenyl)propionic acid (Ibuprofen Impurity K) is a degradation product arising from oxidative and thermal treatments of Ibuprofen which is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain from various conditions such as headache, dental pain or menstrual cramps. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2. This product can be used as a working standard or secondary analytical reference standard. It can also be used as an organic building block and intermediate for synthesis.

Product References

(1) P.A. Asmus, et al.; J. Chromatogr. A 331, 169 (1985) | (2) G. Caviglioli, et al.; J. Pharm. Biomed. Anal. 30, 499 (2002) | (3) M. Gaydou, et al.; JACS 139, 12161 (2017) | (4) Z. Han, et al.; Chromatographia 80, 1353 (2017) | (5) G. Rubasinghege, et al.; Water Res. 131, 22 (2018)

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