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Chemodex
3-Methyladenine
48
CHF
CHF 48.00
In stock
CDX-M0203-M02525 mgCHF 48.00
CDX-M0203-M100100 mgCHF 133.00
CDX-M0203-M250250 mgCHF 291.00
| Product Details | |
|---|---|
| Synonyms | 3-MA; 3MeA; 6-Amino-3-methylpurine; NSC 66389 |
| Product Type | Chemical |
| Properties | |
| Formula | C6H7N5 |
| MW | 149.15 |
| CAS | 5142-23-4 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in DMSO (10 mg/ml), water (5 mg/ml), DMF (10 mg/ml) or ethanol. |
| Identity | Determined by NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | FSASIHFSFGAIJM-UHFFFAOYSA-N |
| Smiles | CN1C=NC(N)=C2N=CN=C12 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Used to inhibit and study the mechanism of autophagy (lysosomal self-degradation) and apoptosis under various conditions. Inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K).
Product References
(1) L.H. Caro, et al.; Eur. J. Biochem. 175, 325 (1988) | (2) E.L. Eskelinen, et al.; Traffic. 3, 878 (2002) | (3) A. Beugnet, et al.; Biochem. J. 372, 555 (2003) | (4) K. Hirosako, et al.; BBRC 316, 845 (2004) | (5) N. Canu, et al.; J. Neurochem. 92, 1228 (2005)
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