3-Methyladenine

CHF 45.00
In stock
CDX-M0203-M02525 mgCHF 45.00
CDX-M0203-M100100 mgCHF 125.00
CDX-M0203-M250250 mgCHF 274.00
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Product Details
Synonyms 3-MA; 3MeA; 6-Amino-3-methylpurine; NSC 66389
Product Type Chemical
Properties
Formula C6H7N5
MW 149.15
CAS 5142-23-4
Source/Host Chemicals Synthetic
Purity Chemicals ≥98% (HPLC)
Appearance White to off-white powder.
Solubility Soluble in DMSO (10 mg/ml), water (5 mg/ml), DMF (10 mg/ml) or ethanol.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key FSASIHFSFGAIJM-UHFFFAOYSA-N
Smiles CN1C=NC(N)=C2N=CN=C12
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
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Product Specification Sheet
Datasheet Download PDF

Used to inhibit and study the mechanism of autophagy (lysosomal self-degradation) and apoptosis under various conditions. Inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K).

Product References

(1) L.H. Caro, et al.; Eur. J. Biochem. 175, 325 (1988) | (2) E.L. Eskelinen, et al.; Traffic. 3, 878 (2002) | (3) A. Beugnet, et al.; Biochem. J. 372, 555 (2003) | (4) K. Hirosako, et al.; BBRC 316, 845 (2004) | (5) N. Canu, et al.; J. Neurochem. 92, 1228 (2005)

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