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Chemodex
Mangiferin
258
CHF
CHF 258.00
In stock
CDX-M0465-G0011 gCHF 258.00
| Product Details | |
|---|---|
| Synonyms | MGF; 1,3,6,7-Tetrahydroxyxanthone C2-β-D-glucoside; NSC 248870 |
| Product Type | Chemical |
| Properties | |
| Formula |
C19H18O11 |
| MW | 422.34 |
| CAS | 4773-96-0 |
| RTECS | OP1927800 |
| Source/Host Chemicals | Plant |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Light yellow powder. |
| Solubility | Soluble in DMSO (5mg/ml) or DMF (2mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | AEDDIBAIWPIIBD-ZJKJAXBQSA-N |
| Smiles | OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](C2=C(O)C(C(C(C=C(O)C(O)=C3)=C3O4)=O)=C4C=C2O)O1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Mangiferin is a xanthone glucoside that has been found in M. indica with diverse biological activities, including analgesic, antidiabetic, antisclerotic, antimicrobial and antiviral, cardio-, hepato-, and neuroprotective, anti-inflammatory, immunomodulatory, anticancer, as well as radioprotective against X-ray, gamma and UV radiation effects. It is also used in cosmetics, due to antioxidant and UV-protecting properties. The anti-inflammatroy activity is through inhibiting NF-κ and NLRP3 signaling pathways.
Product References
(1) F. Gold-Smith, et al.; Nutrients 8, E396 (2016) (Review) | (2) S. Saha, et al.; Biofactors 42, 459 (2016) (Review) | (3) A.J. Nunez Selles, et al.; Biofactors 42, 475 (2016) (Review) | (4) E.V. Fomenko & Y. Chi; Biofactors 42, 492 (2016) (Review) | (5) M. Imran, et al.; Lipids Health Dis. 16, 84 (2017) (Review) | (6) S. Du, et al.; Mol. Med. Rep. 18, 4775 (2018) (Review) | (7) F. Quadri, et al.; Expert Opin. Ther. Pat. 29, 463 (2019) (Review) | (8) S.T. Feng, et al.; Pharmacol. Res. 146, 104336 (2019) (Review)