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Chemodex
2-Morpholinoethyl isocyanide
168
CHF
CHF 168.00
In stock
CDX-M0701-L01010 mlCHF 168.00
CDX-M0701-L02525 mlCHF 335.00
| Product Details | |
|---|---|
| Synonyms | 4-(2-Isocyanoethyl)morpholine; MEI |
| Product Type | Chemical |
| Properties | |
| Formula | C7H12N2O |
| MW | 140.18 |
| CAS | 78375-48-1 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥98% (GC) |
| Appearance | Colorless to very dark yellow liquid. |
| Solubility | Soluble in chloroform. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | MFRZPLYKVDHOSN-UHFFFAOYSA-N |
| Smiles | [C-]#[N+]CCN1CCOCC1 |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | -20°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
2-Morpholinoethyl isocyanide is a buildig block and intermediate for organic synthesis. The principal synthetic application of 2-morpholinoethyl isocyanide is as a coupling reagent of amino acids to yield peptides. It is a potent coupling reagent for peptide synthesis giving higher yields and less racemization than DCCI. It also reacts with aldehydes or ketones to yield amides, with acids to yield imidazolinium salts, and has been used as a ligand in spectroscopic studies to examine shielding effects. 2-Morpholinoethyl isocyanide can be used for the synthesis of nitrogen acyclic carbene (NAC) complexes to be used as catalysts for the synthesis of phenol and hydration of alkynes. It can also be used as a ligand in bis-cyclometalated iridium complexes for the organic light emitting diodes (OLEDs).
Product References
(1) A.M.L. Hoel & J. Nielsen; Tetrahedr. Lett. 40, 3941 (1999) | (2) K. Dedeian, et al.; Inorg. Chem. 46, 1603 (2007) | (3) A.T. Khan, et al.; Tetrahedr. Lett. 53, 2211 (2012) | (4) H. Osborn & J.F. Schneider; Encyclopedia of Reagents for Organic Synthesis (EROS) (2012) | (5) A. Sagirli, et al.; Tetrahedr. 69, 69 (2013) | (6) A. Sehlinger, et al.; Polym. Chem. 6, 3828 (2015) | (7) M. Hartweg, et al.; Polym. Chem., 9, 482 (2018) | (8) H.W. Liang, et al.; Angew. Chem. Int. Ed. Engl. 57, 5720 (2018) | (9) M.D. Ambule, et al.; Chem. Commun. 55, 10872 (2019)