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Chemodex
Neohesperidin dihydrochalcone
Product Details | |
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Synonyms | NHDC; Neohesperidin DC; Neohesperidin DHC; 1-(4-((2-O-[6-Deoxy-α-L-mannopyranosyl]-β-D-glucopyranosyl)oxy)-2,6-dihydroxyphenyl)-3-[3-hydroxy-4-methoxyphenyl]-1-propanone |
Product Type | Chemical |
Properties | |
Formula | C28H36O15 |
MW | 612.58 |
CAS | 20702-77-6 |
RTECS | LZ5785000 |
Source/Host Chemicals | Semisynthetic |
Purity Chemicals | ≥97% (HPLC) |
Appearance | Off-white powder. |
Solubility | Soluble in methanol. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | ITVGXXMINPYUHD-CUVHLRMHSA-N |
Smiles | COC1=CC=C(C=C1O)CCC(C2=C(C=C(C=C2O)O[C@@H]([C@@H]3O[C@@H]([C@@H]4O)O[C@H]([C@@H]([C@H]4O)O)C)O[C@@H]([C@H]([C@@H]3O)O)CO)O)=O |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
Neohesperidin dihydrochalcone is a flavonoid sweetening agent with potent antioxidant activity. It is a preparation from Naringen, a flavanone glycoside occurring naturally in grapefruit. It is used as an artifical sweetener, especially in chewing gum and dentifrices. In food it is used as a flavour enhancer in concentrations of around 4-5 parts per million (ppm) and as an artificial sweetener at around 15-20 ppm. Pharmaceutical companies use it reducing the bitterness of pharmacological drugs in tablet form, and it has been used for livestock feed as a means of reducing feeding time. It is also widely favoured for use in otherwise naturally bitter products. As a flavour enhancer, NHDC is used in a wide range of products and is indicated by the E number E 959. It is noted particularly for enhancing sensory effects.
(1) G.E. Inglett, et al.: J. Food Sci. 34, 101 (1969) | (2) J.F. Fisher; J. Agric. Food Chem. 25, 682 (1977) | (3) P.J. Pratter; Perfum. Flavor. 5, 12 (1981) | (4) B.A.R. Lina, et al.; Food Chem. Toxicol. 28, 507 (1990) | (5) J.-M. Choi, et al.; Biol. Pharm. Bull. 30, 324 (2007)