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Chemodex
Nervonic acid
45
CHF
CHF 45.00
In stock
CDX-N0171-M100100 mgCHF 45.00
| Product Details | |
|---|---|
| Synonyms | FA 24:1; cis-15-Tetracosenoic acid; Selacholeic acid |
| Product Type | Chemical |
| Properties | |
| Formula | C24H46O2 |
| MW | 366.62 |
| CAS | 506-37-6 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥98% (NMR) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in DMSO (20mg/ml), DMF (20mg/ml), ethanol (10mg/ml) or chloroform (50 mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | GWHCXVQVJPWHRF-KTKRTIGZSA-N |
| Smiles | CCCCCCCC/C=C\CCCCCCCCCCCCCC(O)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Nervonic acid is a very long chain fatty acid. It is enriched in nervous tissue and is particularly abundant in sphingolipids, such as sphingomyelin in the myelin sheath of nerve fibers. This myelin sheath is essential for efficient nerve impulse transmission. Nervonic acid may play a role in brain development and neurodegenerative diseases. Nervonic acid is poorly produced in demyelinating disorders, including multiple sclerosis and adrenoleukodystrophy, suggesting that dietary supplementation may be beneficial. Nervonic acid also binds and inhibits DNA polymerase β and HIV-1 reverse transcriptase.
Product References
(1) E.L. Hirvisalo & O. Renkonen; J. Lipid Res. 11, 54 (1970) | (2) J.R. Sargent, et al.; Med. Hypotheses 42, 237 (1994) | (3) N. Kasai, et al.; J. Biochem. 132, 819 (2002) | (4) D.C. Taylor, et al.; Plant Biotechnol. J. 7, 925 (2009) | (5) Q. Li, et al.; Food Chem. 301, 125286 (2019) (Review) | (6) N.V. Phung, et al.; Ctir. Rev. Food Sci. Nutr. (2023) (Review) | (7) M. Namiecinska, et al.; Int. J. Mol. Sci. 25, 3792 (2024) (Review)