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Chemodex
(S)-5-Bromonaproxen
Product Details | |
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Synonyms | Naproxen Impurity C; (αS)-5-Bromo-6-methoxy-α-methyl-2-naphthaleneacetic acid; (2S)-2-(5-Bromo-6-methoxy-2-naphthyl)propionic acid |
Product Type | Chemical |
Properties | |
Formula | C14H13BrO3 |
MW | 309.16 |
CAS | 84236-26-0 |
Source/Host Chemicals | Synthetic |
Purity Chemicals | ≥97% (NMR) |
Appearance | Off-white crystalline powder. |
Solubility | Soluble in chloroform. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | JZRWXNBIQCMXSU-QMMMGPOBSA-N |
Smiles | BrC1=C(C=CC([C@@H](C(O)=O)C)=C2)C2=CC=C1OC |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +20°C |
Long Term Storage | +4°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
(S)-5-Bromonaproxen (Naproxen Impurity C) is a brominated metabolite (most probably through reaction with water) from Naproxen which is a non-steroidal anti-inflammatory drug (NSAID) used to in the treatment of pain, menstrual cramps, inflammatory diseases such as rheumatoid arthritis, gout and fever. Ibuprofen is an anti-inflammatory COX inhibitor. This product can be used as a secondary analytical reference standard or as an organic building block and intermediate for synthesis, especially targeted bromination.
(1) C. Giordano, et al.; Tetrahedr. 45, 4243 (1989) | (2) K. Solakyildirim, et al.; Magn. Reson. Chem. 52, 310 (2014) | (3) Y. Satkar, et al.; RSC Adv. 8, 17806 (2018)