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Chemodex
N-Nitrosomorpholine (NMOR)
258
CHF
CHF 258.00
In stock
CDX-N0370-G0011 gCHF 258.00
| Product Details | |
|---|---|
| Synonyms | NMOR; Nitrosomorpholine; NSC-139; BRN 0112139 |
| Product Type | Chemical |
| Properties | |
| Formula | C4H8N2O2 |
| MW | 116.12 |
| CAS | 59-89-2 |
| RTECS | QE7525000 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥98% (GC) |
| Appearance | Yellow clear liquid. |
| Solubility | Soluble in DMSO. Sligthly soluble in methanol. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | ZKXDGKXYMTYWTB-UHFFFAOYSA-N |
| Smiles | O=NN1CCOCC1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
N-Nitrosomorpholine (NMOR) is a nitrosamine and is known to be a potent carcinogen associated with cancer development in animals and humans. NMOR can damage DNA and cause mutations in genes that control cell growth and division. It reacts with DNA in vitro to form genotoxic activity, which may lead to cell death or mutagenesis. NMOR is formed in various industrial processes, including the synthesis of certain chemicals and in the preservation of cosmetic and personal care products. This compound can be used as analytical reference material. NMOR is used as a tumor initiator. It is a reagent for preparing carcinogenic animal diseases model. NMOR has other widespread utilization in laboratory and industrial environments. NMOR exhibits potent oxidizing properties, making it valuable in various applications, including as a bulding block for synthesis, environmental monitoring, and as a reagent in laboratory settings. It serves as a vital component in the synthesis of diverse compounds and functions as an analytical reagent.
Product References
(1) H.S. Taper, et al.; Cancer Res. 31, 913 (1971) | (2) R. Prakin, et al.; Mutat. Res. 21, 155 (1973) | (3) C.E. Kimble, et al.; Mutat. Res. 31, 153 (1975) | (4) K.D. Brunnemann, et al.; Carcinogenesis 3, 693 (1982) | (5) J.B. Morrison & S.S. Hecht; IARC Sci. Publ. 57, 185 (1984) | (6) R.G. Klein, et al.; Exp. Pathol. 40, 189 (1990) | (7) P.A. Munzel, et al.; Biochem. Pharnacol. 42, 365 (1991) | (8) S. Tudzarova-Trajkovska & J. Wesierska-Gadek; J. Cell Biochem. 90, 837 (2003) | (9) S. Robichova, et al.; Chem. Biol. Interact. 148, 163 (2004) | (10) C.M. Glover, et al.; Water Res. 148, 306 (2019) | (11) Y. Li & S.S. Hecht; Int. J. Mol. Sci. 23, 4559 (2022) | (12) M. Bignami, et al.; Efsa J. 21, e07884 (2023)