Chemodex

Octadecyl Rhodamine B chloride

Name: Octadecyl Rhodamine B chloride
Brand: Chemodex
SKU: CDX-O0014
Price: 329.00 CHF
Availability: InStock

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CDX-O0014-M01010 mgCHF 329.00

CDX-O0014-M02525 mgCHF 657.00

Specifications / Handling

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Product Details
Synonyms	R18 Cl; ORBC
Product Type	Chemical
Properties
Formula	C₄₆H₆₇ClN₂O₃
MW	731.5
CAS	65603-19-2
Source/Host Chemicals	Synthetic
Purity Chemicals	≥95% (TLC)
Appearance	Red solid.
Solubility	Soluble in ethanol (10mg/ml) or DMSO.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturer's product datasheet.
InChi Key	NFGODEMQGQNUKK-UHFFFAOYSA-M
Smiles	CCCCCCCCCCCCCCCCCCOC(=O)C1=CC=CC=C1C2=C3C=CC(=[N+](CC)CC)C=C3OC4=C2C=CC(=C4)N(CC)CC.[Cl-]
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
Product Specification Sheet
Datasheet	Download PDF

Scientific Background Information

Product Description

Octadecyl Rhodamine B chloride (R18) is a lipophilic fluorescent dye widely used in membrane biology and cell labeling studies. R18 is used in dequenching assays to monitor liposome fusion or virus-cell membrane fusion. It incorporates into plasma membranes for cell tracking, membrane dynamics, or cell-cell interaction studies. It can be used to label synthetic vesicles to study endocytosis, drug delivery, or membrane trafficking. R18 has also been used as acceptor in FRET studies on liposomes. The fluorescence of octadecyl rhodamine B in membranes is quenched at high dye concentration but is released at dilution. This property makes the dye useful for membrane fusion assays. Spectral Data: λEx/λEm (MeOH) = 556/580nm.

Product-specific References

(1) D. Hoekstra, et al.; Biochem. 23, 5675 (1984) | (2) A. Stutzin, et al.; FEBS Lett. 197, 274 (1986) | (3) D. Hoekstra & K. Klappe K; Biosci. Rep. 6, 953 (1986) | (4) S. Tomlinson, et al.; Biochem. 28, 8303 (1989) | (5) L. Corazzi, et al.; J. Membr. Biol. 112, 123 (1989) | (6) J. Arnhold, et al.; Biochim. Biophys. Acta 1191, 375 (1994) | (7) T. Reda, et al.; Mol. Membr. Biol. 12, 271 (1995) | (8) H. Hyogo, et al.; Dig. Dis. Sci. 44, 1662 (1999) | (9) A.A. Vallejo & M.S. Fernandez; Arch. Biochem. Biophys. 480, 1 (2008) | (10) I. Trikash, et al.; Chem. Phys. Lipids 163, 778 (2010) | (11) T. Tian, et al.; J. Cell Physiol. 228, 1487 (2013) | (12) Y.M.D. Gnopo & D. Putnam; Methods 177, 74 (2020)

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