Chemodex

N-Octanoyl-L-homoserine lactone

CHF 68.00

In stock

CDX-O0038-M0055 mgCHF 68.00

CDX-O0038-M05050 mgCHF 407.00

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Product Details
Synonyms	N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-octanamide; C8-HSL; OHL
Product Type	Chemical
Properties
Formula	C₁₂H₂₁NO₃
MW	227.3
CAS	147852-84-4
Source/Host Chemicals	Synthetic.
Purity Chemicals	≥98% (NMR)
Appearance	White powder.
Solubility	Soluble in DMSO and dimethylformamide (approx. 30mg/ml).
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	JKEJEOJPJVRHMQ-JTQLQIEISA-N
Smiles	CCCCCCCC(=O)N[C@H]1CCOC1=O
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Keep cool and dry. Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at +4°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

N-Octanoyl-L-homoserine lactone (C8-HSL) is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. The applications of this molecule include infection prevention and regulation of virulence in general and in cystic fibrosis.

Product References

(1) J.T. Hodgkinson; Tetrahedron Lett. 52, 3291 (2011) | (2) G.D. Geske; JACS 127, 12762 (2005) | (3) A. Kuo, et al.; J. Bacteriol. 176, 7558 (1994) | (4) J.K. Lithgow, et al.; Mol. Microbiol. 37, 81 (2000) | (5) K.H. McClean, et al.; Microbiol. 143, 3703 (1997) | (6) K. Riedel, et al.; Microbiol. 147, 3249 (2001) | (7) M.K. Winson, et al.; PNAS 92, 9427 (1995)

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