N-Octanoyl-L-homoserine lactone

CHF 68.00
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CDX-O0038-M0055 mgCHF 68.00
CDX-O0038-M05050 mgCHF 407.00
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Product Details
Synonyms N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-octanamide; C8-HSL; OHL
Product Type Chemical
Formula C12H21NO3
MW 227.3
CAS 147852-84-4
Source/Host Chemicals Synthetic.
Purity Chemicals ≥98% (NMR)
Appearance White powder.
Solubility Soluble in DMSO and dimethylformamide (approx. 30mg/ml).
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

N-Octanoyl-L-homoserine lactone (C8-HSL) is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. The applications of this molecule include infection prevention and regulation of virulence in general and in cystic fibrosis.

Product References

(1) J.T. Hodgkinson; Tetrahedron Lett. 52, 3291 (2011) | (2) G.D. Geske; JACS 127, 12762 (2005) | (3) A. Kuo, et al.; J. Bacteriol. 176, 7558 (1994) | (4) J.K. Lithgow, et al.; Mol. Microbiol. 37, 81 (2000) | (5) K.H. McClean, et al.; Microbiol. 143, 3703 (1997) | (6) K. Riedel, et al.; Microbiol. 147, 3249 (2001) | (7) M.K. Winson, et al.; PNAS 92, 9427 (1995)

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