N-Octanoyl-L-homoserine lactone

CHF 64.00
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CDX-O0038-M0055 mgCHF 64.00
CDX-O0038-M05050 mgCHF 383.00
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Product Details
Synonyms N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-octanamide; C8-HSL; OHL
Product Type Chemical
Properties
Formula C12H21NO3
MW 227.3
CAS 147852-84-4
Source/Host Chemicals Synthetic.
Purity Chemicals ≥98% (NMR)
Appearance White powder.
Solubility Soluble in DMSO and dimethylformamide (approx. 30mg/ml).
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key JKEJEOJPJVRHMQ-JTQLQIEISA-N
Smiles CCCCCCCC(=O)N[C@H]1CCOC1=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
Documents
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Product Specification Sheet
Datasheet Download PDF

N-Octanoyl-L-homoserine lactone (C8-HSL) is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. The applications of this molecule include infection prevention and regulation of virulence in general and in cystic fibrosis.

Product References

(1) J.T. Hodgkinson; Tetrahedron Lett. 52, 3291 (2011) | (2) G.D. Geske; JACS 127, 12762 (2005) | (3) A. Kuo, et al.; J. Bacteriol. 176, 7558 (1994) | (4) J.K. Lithgow, et al.; Mol. Microbiol. 37, 81 (2000) | (5) K.H. McClean, et al.; Microbiol. 143, 3703 (1997) | (6) K. Riedel, et al.; Microbiol. 147, 3249 (2001) | (7) M.K. Winson, et al.; PNAS 92, 9427 (1995)

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