Chemodex

1-Pyrenebutanoic acid hydrazide

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Product Details
Synonyms PBH; 1-Pyrenebutyric hydrazide; Pyrenebutyrylhydrazine
Product Type Chemical
Properties
Formula C20H18N2O
MW 302.37
CAS 55486-13-0
Source/Host Chemicals Synthetic
Purity Chemicals ≥97% (HPLC)
Appearance White to off-white powder.
Solubility Soluble in DMSO.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturer's product datasheet.

InChi Key SOPPDVMSOKMZOC-UHFFFAOYSA-N
Smiles O=C(NN)CCCC1=CC=C2C=CC3=CC=CC=4C=CC1=C2C34
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at RT.
Documents
Product Specification Sheet
Datasheet Download PDF
Description
1-Pyrenebutanoic acid hydrazide (PBH) is a fluorescent labeling reagent commonly used in biochemistry and molecular biology. Spectral Data: λex 340nm, λem 375nm (MeOH). The hydrazide group reacts with carbonyl groups (like aldehydes or ketones) to form hydrazones. This makes PBH useful for labeling oxidized sugars, glycoproteins, or carbonylated biomolecules. It can be used to modify surfaces (e.g., glass or nanoparticles) for biosensing applications. Also used in the derivatization of proteins, carbohydrates, or lipids that have been oxidized to expose reactive carbonyls. PBH is utilized in developing advanced optical materials, where its fluorescence properties can enhance the detection sensitivity of various biological and chemical systems.
Product References
(1) S.A. Reines & C.R. Cantor; Nucleic Acids Res. 1, 767 (1974) | (2) P. Koenig, et al.; Biopolymers 16, 2231 (1977) | (3) N. Shambaugh & E. Fujimori; Biopolymers 21, 79 (1982) | (4) D. Sugahara, et al.; Anal. Sci. 19, 167 (2003) | (5) H. Yoshida, et al.; Anal. Chim. Acta 534, 177 (2005) | (6) F.V Mansano, et al.; Anal. Chem. 82, 6775 (2010) | (7) F. Novio, et al.; Chem. Eur. J. 20, 15443 (2014) | (8) R.W. Sabnis; Handbook of Fluorescent Dyes and Probes 334 (2015)
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