Chemodex

1,10-Phenanthroline monohydrate

CHF 52.00
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CDX-P0147-G0055 gCHF 52.00
CDX-P0147-G02525 gCHF 168.00
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Product Details
Synonyms o-Phenanthroline monohydrate; 4,5-Diazaphenanthrene monohydrate; β-Phenanthroline monohydrate
Product Type Chemical
Properties
Formula C12H8N2 . H2O
MW 198.22
CAS 5144-89-8
RTECS SF8437000
Source/Host Chemicals Synthetic
Purity Chemicals ≥97% (NMR)
Appearance White to off-white powder.
Solubility Soluble in DMSO (20mg/ml) or ethanol (20mg/ml).
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key PPQJCISYYXZCAE-UHFFFAOYSA-N
Smiles C12=CC=CN=C1C3=C(C=CC=N3)C=C2.O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +20°C
Handling Advice Keep under inert gas.
Very hygroscopic.
Use/Stability Stable for at least 2 years after receipt when stored at RT.
Documents
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Product Specification Sheet
Datasheet Download PDF
Description

Hydrate form of 1,10-Phenanthroline. 1,10-Phenanthroline is a heterocyclic organic compound, which forms complexes with metal ions. It is a versatile ligand employed in the spectrophotometric determination of metals and photocatalytic reduction of carbon dioxide. The complexes that are build have wide applications in biochemistry, catalysis and analytical chemistry. 1,10-Phenanthroline is a ligand used in a mild, copper (II)-catalyzed cross-coupling of organoboronic acids and sulfinate salts leading to aryl- and alkenylsulfones. It is a conventional chelator to study its efficacy in Fenton's reaction-luminol chemiluminescence system. 1,10-Phenanthroline enhances hPSC differentiation into cranial placode cells and is known as a non-specific matrix metalloproteinase (MMP) inhibitor. 1,10-Phenanthroline is also used as a building block for metallomacrocycles and other biological active compounds, such as anti-cancer agents.

Product References

(1) G. Hoyer, et al.; Scand. J. Clin. Lab Invest. 2, 125 (1950) | (2) M.M. Jones & D.O. Johnston; Nature 216, 509 (1967) | (3) K. Kobashi; Biochim. Biophys. Acta 158, 239 (1968) | (4) H.M. Butler, et al.; Aust. J. Exp. Biol. Med. Sci. 47, 541 (1969) | (5) M. Kito & R. Urade; Met. Ions Biol. Syst. 38, 187 (2001) (Review) | (6) M. McCann, et al.; Curr. Med. Chem. 19, 2703 (2012) (Review) | (7) J. Tchieu, et al.; Cell Stem Cell 21, 399 (2017) | (8) N. Georgi, et al.; J. Tissue Eng. Regen. Med. 11, 724 (2017) | (9) S. Masuri, et al.; Molecules 27, 49 (2021) (Review) | (10) W.A. Souza, et al.; J. Inorg. Biochem. 237, 111993 (2022) | (11) U. Bildziukevich, et al.; Org. Biomol. Chem. 20, 8157 (2022) | (12) M.M. Cetin, et al.; Front. Pharmacol. 13, 980479 (2022) | (13) N.A. Ashashi, et al.; ACS Omega 7, 41370 (2022) | (14) D. Zhang, et al.; Spectrochim. Acta A Mol. Biomol. Spectrosc. 295, 122608 (2023)

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