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Chemodex
Procaine hydrochloride
41
CHF
CHF 41.00
In stock
CDX-P0182-M250250 mgCHF 41.00
| Product Details | |
|---|---|
| Synonyms | 4-Aminobenzoic acid 2-diethylaminoethyl ester; p-Aminobenzoic acid diethylaminoethyl ester hydrochloride; Novocaine hydrochloride |
| Product Type | Chemical |
| Properties | |
| Formula | C13H20N2O2 . HCl |
| MW | 272.77 |
| CAS | 51-05-8 |
| RTECS | DG2275000 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in water or ethanol. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | HCBIBCJNVBAKAB-UHFFFAOYSA-N |
| Smiles | NC1=CC=C(C(OCC[NH+](CC)CC)=O)C=C1.[Cl-] |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Procaine is a sodium channel blocker, commonly used as an anesthetic agent and a variety of other inhibitiory effects. It is also useful as a painkiller to prevent or relieve pain for short periods, such as during dental procedures. In skeletal muscle, Procaine has been reported to inhibit calcium-induced calcium release (CICR) and to inhibit nicotinic acetylcholine receptors. It has been shown to be a DNA methylation inhibitor with anti-tumor activity. Inhibited also HERG channels. Can be used as an analytical reference compound, since procaine is used as an adulterant in illicit drugs.
Product References
(1) S. Epstein & N.W. Chilton; Oral Surg. Oral Med. Oral Pathol. 12, 93 (1959) | (2) R. Werdehausen, et al.; Br. J. Anaesth. 103, 711 (2009) | (3) Z. Gao, et al.; Oncol. Rep. 22, 1479 (2009) | (4) M. Endo; Physiol. Rev. 89, 1153 (2009) | (5) H. Wang, et al.; Eur. J. Pharmacol. 630, 29 (2010) | (6) R. Gal & F. Libersat; PLoS ONE 5, e10019 (2010) | (7) C. Cole, et al.; CUT (2010) | (8) N. Wang, et al.; J. Pharmacol. Sci. 123, 25 (2013) | (9) C. Li, et al.; Oncol. Res. 26, 209 (2018) | (10) Y.C. Li, et al.; J. Cell Biochem. 119, 2440 (2018)