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Chemodex
trans-Piceatannol
Product Details | |
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Synonyms | 3,3',4,5'-Stilbenetetrol; 3,3',4,5'-Tetrahydroxy-trans-stilbene; Astringenin; CCRIS 9289; NSC365798; NSC622471; 3-Hydroxyresveratrol |
Product Type | Chemical |
Properties | |
Formula |
C14H12O4 |
MW | 244.24 |
CAS | 10083-24-6 |
Source/Host Chemicals | Plant |
Purity Chemicals | ≥98% (HPLC) |
Appearance | Light tan to yellow powder. |
Solubility | Soluble in DMSO (10 mg/mL) or ethanol (10 mg/mL). |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | CDRPUGZCRXZLFL-OWOJBTEDSA-N |
Smiles | OC1=CC(/C=C/C2=CC(O)=CC(O)=C2)=CC=C1O |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +20°C |
Long Term Storage | +4°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
Piceatannol is a resveratrol analog with anticancer, anti-inflammatory, antioxidant, neuroprotective and cardioprotective properties. It is a spleen tyrosine kinase (Syk) inhibitor, however it exhibits antiproliferative activity by inhibiting a wide range of tyrosine and serine/threonine protein kinases, including Syk, p56lck, PKA, PKC, MLCK, CDPK, JNK and PI3K. It suppresses NF-κ activation through inhibition of IκBα kinase and NLRP3 activation. It is an apoptosis and autophagy inducer, cell cycle inhibitor, activator of SIRT1 and also inhibits adipogenesis.
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