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Chemodex
Polydatin
41
CHF
CHF 41.00
In stock
CDX-P0596-G0011 gCHF 41.00
| Product Details | |
|---|---|
| Synonyms | Piceid; Reservatrol-3-β-mono-D-glucoside; Resveratrol 3-O-β-D-glucopyranoside; 3,4'-5-Trihydroxystilbene-3-β-D-glucopyranoside |
| Product Type | Chemical |
| Properties | |
| Formula |
C20H22O8 |
| MW | 390.38 |
| CAS | 65914-17-2 |
| Source/Host Chemicals | Plant |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to yellow powder. |
| Solubility | Soluble in DMSO (30mg/ml), DMF (50mg/ml) or ethanol (30mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | HSTZMXCBWJGKHG-CUYWLFDKSA-N |
| Smiles | OC1=CC(/C=C/C2=CC=C(O)C=C2)=CC(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Polydatin is a natural stilbene with antioxidant, anti-inflammatory, anticancer, neuroprotective, cardioprotective, anti-osteoporotic and antilipidemic properties. It has been shown to inhibit NF-κ signaling pathway and the NLRP3 inflammasome activation. It is an apoptosis and autophagy inducer, cell cycle inhibitor, activator of SIRT1 and also inhibits adipogenesis.
Product References
(1) J. Du, et al.; Phytomedicine 16, 652 (2009) | (2) Q. Miao, et al.; Phytomedicine 19, 8 (2011) | (3) H. Ji, et al.; Brain Res. Bull. 87, 50 (2012) | (4) Q.H. Du, et al.; Pharm. Biol. 51, 1347 (2013) (Review) | (5) Y. Zhang, et al.; Oncol. Lett. 7, 295 (2014) | (6) J. Sun, et al.; Mol. Med. Rep. 10, 3047 (2014) | (7) J. Hao, et al.; Eur. J. Pharmacol. 745, 152 (2014) | (8) H.L. Wang, et al.; Phytomedicine 22, 553 (2015) | (9) Y. Chen, et al.; Mol. Neurodegener. 10, 4 (2015) | (10) Z. Zeng, et al.; J. Surg. Res. 198, 192 (2015) | (11) Z. Zeng, et al.; Oxid. Med. Cell Longev. 2015, 965961 (2015) | (12) Y. Ma, et al.; Int. J. Mol. Med. 37, 1652 (2016) | (13) Q.L. Zhou, et al.; Mol. Med. Rep. 14, 1865 (2016) | (14) J. Jin, et al.; Adv. Exp. Med. Biol. 923, 57 (2016) | (15) B. Yang & S. Zhao; Onco. Targets Ther. 10, 935 (2017) | (16) J. Zou, et al.; Biomed. Pharmacother. 108, 130 (2018) | (17) Y.L. Jin, et al.; Onco. Targets Ther. 11, 8185 (2018) | (18) J. Tang, et al.; J. Cell Biochem. 120, 10137 (2019)