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Chemodex
Polydatin
As low as
41
CHF
CHF 41.00
In stock
Only %1 left
CDX-P0596-G0011 gCHF 41.00
Specifications / Handling
| Product Details | |
|---|---|
| Synonyms | Piceid; Reservatrol-3-β-mono-D-glucoside; Resveratrol 3-O-β-D-glucopyranoside; 3,4'-5-Trihydroxystilbene-3-β-D-glucopyranoside |
| Product Type | Chemical |
| Properties | |
| Formula |
C20H22O8 |
| MW | 390.38 |
| CAS | 65914-17-2 |
| Source/Host Chemicals | Plant |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to yellow powder. |
| Solubility | Soluble in DMSO (30mg/ml), DMF (50mg/ml) or ethanol (30mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | HSTZMXCBWJGKHG-CUYWLFDKSA-N |
| Smiles | OC1=CC(/C=C/C2=CC=C(O)C=C2)=CC(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Scientific Background Information
Product Description
Polydatin is a natural stilbene with antioxidant, anti-inflammatory, anticancer, neuroprotective, cardioprotective, anti-osteoporotic and antilipidemic properties. It has been shown to inhibit NF-κ signaling pathway and the NLRP3 inflammasome activation. It is an apoptosis and autophagy inducer, cell cycle inhibitor, activator of SIRT1 and also inhibits adipogenesis.
Product-specific References
(1) J. Du, et al.; Phytomedicine 16, 652 (2009) | (2) Q. Miao, et al.; Phytomedicine 19, 8 (2011) | (3) H. Ji, et al.; Brain Res. Bull. 87, 50 (2012) | (4) Q.H. Du, et al.; Pharm. Biol. 51, 1347 (2013) (Review) | (5) Y. Zhang, et al.; Oncol. Lett. 7, 295 (2014) | (6) J. Sun, et al.; Mol. Med. Rep. 10, 3047 (2014) | (7) J. Hao, et al.; Eur. J. Pharmacol. 745, 152 (2014) | (8) H.L. Wang, et al.; Phytomedicine 22, 553 (2015) | (9) Y. Chen, et al.; Mol. Neurodegener. 10, 4 (2015) | (10) Z. Zeng, et al.; J. Surg. Res. 198, 192 (2015) | (11) Z. Zeng, et al.; Oxid. Med. Cell Longev. 2015, 965961 (2015) | (12) Y. Ma, et al.; Int. J. Mol. Med. 37, 1652 (2016) | (13) Q.L. Zhou, et al.; Mol. Med. Rep. 14, 1865 (2016) | (14) J. Jin, et al.; Adv. Exp. Med. Biol. 923, 57 (2016) | (15) B. Yang & S. Zhao; Onco. Targets Ther. 10, 935 (2017) | (16) J. Zou, et al.; Biomed. Pharmacother. 108, 130 (2018) | (17) Y.L. Jin, et al.; Onco. Targets Ther. 11, 8185 (2018) | (18) J. Tang, et al.; J. Cell Biochem. 120, 10137 (2019)