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Chemodex
Salicin
102
CHF
CHF 102.00
In stock
CDX-S0001-G02525 gCHF 102.00
CDX-S0001-G100100 gCHF 305.00
| Product Details | |
|---|---|
| Synonyms | D-(-)-Salicin; 2-(Hydroxymethyl)phenyl-β-D-glucopyranoside; Salicoside; Salicyl alcohol glucoside; Saligenin β-D-glucoside; NSC 5751 |
| Product Type | Chemical |
| Properties | |
| Formula |
C13H18O7 |
| MW | 286.28 |
| CAS | 138-52-3 |
| RTECS | LZ5901700 |
| Source/Host Chemicals | Isolated from plant source. |
| Purity Chemicals | ≥99% (HPLC) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in water (10mg/ml), DMSO (20mg/ml) or DMF (30mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | NGFMICBWJRZIBI-UJPOAAIJSA-N |
| Smiles | OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC2=CC=CC=C2CO)O1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at RT. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Salicin is an alcoholic β-glucoside derived from willow bark that produces antioxidant and anti-inflammatory (including analgesic and antipyretic) effects very similar to that of aspirin. It acts as a non-selective COX inhibitor for COX-1 and COX-2. It has been used in the treatment of rheumatism. Shown to inhibit angiogenesis by blocking the ROS-ERK pathways and to have in vivo anticancer activity.
Product References
(1) T. Maclagan; Br. Med. J. 1, 627 (1876) | (2) T.D. Warner, et al.; PNAS 96, 7563 (1999) | (3) I. Wagner & L. Heide; J. Rheumatol. 30, 1125 (2003) | (4) A.L. Blobaum & L.J. Marnett; J. Med. Chem. 50, 1425 (2007) | (5) N. Verma, et al.; Inflamm. Res. 63, 161 (2014) | (6) C.S. Kong, et al.; Phytother. Res. 28, 1246 (2014) | (7) Y. Li, et al.; Int. Immunopharmacol. 26, 286 (2015) | (8) M. Sabaa, et al.; Naunyn Schmiedebergs Arch. Pharmacol. 390, 1061 (2017)