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Chemodex
Sarcosine
CHF 0.00
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| Product Details | |
|---|---|
| Synonyms | N-Methylglycine; H-NMeGly-OH; 2-(Methylamino)acetic acid |
| Product Type | Chemical |
| Properties | |
| Formula | C3H7NO2 |
| MW | 89.09 |
| CAS | 107-97-1 |
| RTECS | VQ2897000 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥99% (T) |
| Appearance | Colorless or white powder or crystals. |
| Solubility | Soluble in water (10mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | FSYKKLYZXJSNPZ-UHFFFAOYSA-N |
| Smiles | CNCC(O)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at RT. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Sarcosine (N-methylglycine) is a naturally occurring amino acid derivative that plays an important role as an intermediate in glycine and choline metabolism. It functions as a modulator of N-methyl-D-aspartate (NMDA) receptor activity a selective inhibitor of glycine transporter 1 (GlyT1), thereby enhancing synaptic glycine levels and NMDA receptor function. Sarcosine is widely used in neuroscience research, particularly for its potential therapeutic applications in schizophrenia, depression and cognitive disorders. Sarcosine serves also as a diagnostic biomarker, notably in prostate cancer screening, where elevated levels in biological fluids are linked to disease progression. Additionally, it is used in biochemical assays, metabolic studies, and as a building block in peptide synthesis.
Product References
(1) G. Tsai, et al.; Biol. Psychiatry 55, 452 (2004) | (2) H.X. Zhang, et al.; Neuropharmacol. 57, 551 (2009) | (3) H.X. Zhang, et al.; J. Physiol. 587, 3207 (2009) | (4) A. Sreekumar, et al.; Nature 457, 910 (2009) | (5) W. Wang, et al.; Amino Acids 45, 463 (2013) | (6) N. Cernei, et al.; Int. J. Mol. Sci. 14, 13893 (2013)