Chemodex

Sarcosine methyl ester hydrochloride

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Product Details
Synonyms N-Methylglycine methyl ester hydrochloride; H-Sar-OMe HCl
Product Type Chemical
Properties
Formula C4H9NO2 . HCl
MW 139.58
CAS 13515-93-0
Source/Host Chemicals Synthetic
Purity Chemicals ≥97% (T)
Appearance White to faint beige powder.
Solubility Soluble in water.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key HQZMRJBVCVYVQA-UHFFFAOYSA-N
Smiles CNCC(OC)=O.Cl
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +4°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
Documents
Product Specification Sheet
Datasheet Download PDF
Description
Sarcosine methyl ester hydrochloride is a stable, crystalline salt derivative of sarcosine widely employed as a versatile intermediate in organic synthesis and peptide chemistry. It serves as a protected form of sarcosine, facilitating incorporation into peptide chains and enabling the preparation of N-methylated amino acid derivatives, which are important for studying protein structure, function and stability. It is used in the design of peptidomimetics and bioactive compounds due to its ability to modulate conformational properties and enhance resistance to enzymatic degradation. It is a useful building block in synthesis and important in medicinal chemistry, peptide research and advanced materials development.
Product References
(1) M. Sheinblatt; J. Chem. Phys. 1962, 363103 (1962) | (2) C. Alarcon, et al.; Biosci. Rep. 5, 581 (1985) | (3) A. Sener, et al.; Endocrinol. 117, 237 (1985) | (4) D. Zhou, et al.; J. Phys. Chem. 100, 3150 (1996) | (5) D.O.H. Teare, et al.; J. Phys. Chem. B 109, 20923 (2005) | (6) A. Pedrini, et al.; Molecules 23, 2670 (2018)
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