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Chemodex
2,2'-Dipyridyldisulfide
45
CHF
CHF 45.00
In stock
CDX-Y1024-G0055 gCHF 45.00
CDX-Y1024-G02525 gCHF 122.00
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| Product Details | |
|---|---|
| Synonyms | 2,2'-Dipyridyldisulfide; 2,2'-Dipyridyl disulfide; 2,2'-Dithiodipyridine; Di(pyridin-2-yl) disulphide; 2-PDS; DPS; NSC677438; NSC94055 |
| Product Type | Chemical |
| Properties | |
| Formula | C10H8N2S2 |
| MW | 220.31 |
| CAS | 09.03.2127 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥99% (GC) |
| Appearance | White to off-white powder or crystals. |
| Solubility | Soluble in DMSO. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | HAXFWIACAGNFHA-UHFFFAOYSA-N |
| Smiles | C1(SSC2=NC=CC=C2)=CC=CC=N1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
2,2'-Dipyridyldisulfide is a useful colorimetric reagent for the determination of sulfhydryl groups (Molar absorptivity: >14,000; ~235nm). It is used to determine cholinesterase in whole blood by spectrophotometric method. 2,2'-Dipyridyldisulfide is a common reagent in peptide chemistry, often used in oxidation�reduction condensations to form peptide bonds or in coupling reactions to form disulfide-linked heterodimers. It is used for preparation of amino acid active esters and the thio esters of phosphoric acid. It acts as a peptide coupling reagent and as an oxidizing agent. It is also used for the activation of glycosides.
Product References
(1) D.R. Grassetti 6 J.F. Murray Jr., Arch. Biochem. Biophys. 119, 41 (1967) | (2) R.E. Humphrey, et al.; Anal. Chem. 42, 698 (1970) | (3) R.E. Humphrey & W. Hinze; Talanta 18, 491 (1971) | (4) T. Uete, et al.; Clin. Chem. 18, 454 (1972) | (5) T.M. Kitson; Biochem. J. 207, 81 (1982) | (6) S. Futaki & K. Kitagawa; Tetrahedron Lett. 35. 1267 (1994) | (7) J.J. Ceron, et al.; J. AOAC Int. 79, 757 (1996) | (8) K. Maruyama, et al.; Peptides 20, 881 (1999) | (9) D. Singh, et al.; Eur. J. Org. Chem. 2010, 2661 (2010) | (10) H. Gokce & S, Bahceli; Spectrochim. Acta A Mol. Biomol. Spectrosc. 114, 61 (2013)