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Chemodex
Zinpyr-1
Product Details | |
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Synonyms | ZP-1; 4′,5′-Bis[bis(2-pyridylmethyl)aminomethyl]-2′,7′-dichlorofluorescein |
Product Type | Chemical |
Properties | |
Formula |
C46H36Cl2N6O5 |
MW | 823.72 |
CAS | 288574-78-7 |
Source/Host Chemicals | Synthetic. |
Purity Chemicals | ≥98% (HPLC) |
Appearance | Salmon pink powder. |
Solubility | Soluble in DMSO (1mg/ml). |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | QZKKSPLNXQJQRQ-UHFFFAOYSA-N |
Smiles | OC1=C(CN(CC2=CC=CC=N2)CC2=NC=CC=C2)C2=C(C=C1Cl)C1(OC(=O)C3=C1C=CC=C3)C1=CC(Cl)=C(O)C(CN(CC3=CC=CC=N3)CC3=NC=CC=C3)=C1O2 |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Membrane permeable fluorescein-based probe suitable for the fluorometric detection of Zn2+. In living cells Zinpyr-1 mainly stains the Golgi or a Golgi-associated vesicle. It undergoes a shift in excitation from 515 to 507nm with increasing zinc concentrations using an emission filter over 513-558nm. A stock solution of 1mM (823µg/ml) should be prepared to stain brain sections. This stock solution can be further diluted in 0.9% saline to get a working solution with a final concentration of 10-20μM.
(1) G.K. Walkup, et al; JACS 122, 5644 (2000) | (2) S.C. Burdette, et al.; JACS 123, 7831 (2001) | (3) C.C. Woodproof, et al.; Chem. Biol. 11, 1659 (2004) | (4) M. Malavolta, et al.; Cytometry Part A 69A, 1043 (2006) | (5) S.A. Sinclair, et al.; New Phytologist 174, 39 (2007)