Zinquin ethyl ester

CHF 81.00
In stock
CDX-Z0013-M0011 mgCHF 81.00
CDX-Z0013-M0055 mgCHF 204.00
CDX-Z0013-M05050 mgCHF 1'083.00
More Information
Product Details
Synonyms 2-[[2-Methyl-8-[[(4-methylphenyl)sulfonyl]amino]-6-quinolinyl]oxy]-acetic acid ethyl ester
Product Type Chemical
Formula C21H22N2O5S
MW 414.47
CAS 181530-09-6
Source/Host Chemicals Synthetic.
Purity Chemicals ≥99% (HPLC)
Appearance White solid.
Solubility Soluble in DMSO. Slightly soluble in water.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Smiles CCOC(=O)COC1=CC(NS(=O)(=O)C2=CC=C(C)C=C2)=C2N=C(C)C=CC2=C1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Zinquin ethyl ester is a cell-permeable, lipophilic, zinc-sensitive, fluorescent derivative of Zinquin. Cleavage of the ethyl ester group via cytosolic esterases in living cells impedes its efflux across the plasma membrane. It is selective for Zn (II) in the presence of physiological concentrations of Ca (II) and Mg (II) ions. Fluorescence of Zinquin ethyl ester is enhanced upon binding Zn (II), but the probe does not demonstrate a shift or change in emission wavelength. The probe is UV-excitable and emits in the blue region of the spectrum. Ex(max) 368nm, Em(max) 490nm. Zinquin ethyl ester has been used to monitor intracellular zinc fluxes associated with apoptosis.

Product References

(1) I.B. Mahadevan et al.; Australian Journal of Chemistry 49(5), 561-568 (1996) | (2) J.C. Fahrni & T.V. O'Halloran; JACS 121(49), 11448-11458 (1999) | (3) A.Q. Truong-Tran, et al.; The Journal of Nutrition 130, 1459 (2000) | (3) D. Lu, et al.; Adv. Mater. 31, e1902739 (2019)

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