CCL24 (human):Fc (human) (rec.)

CHF 195.00
In stock
CHI-HF-210CCL24-C01010 µgCHF 195.00
CHI-HF-210CCL24-C05050 µgCHF 380.00
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Product Details
Synonyms Eotaxin-2; C-C Motif Chemokine 24; Eosinophil Chemotactic Protein 2; Myeloid Progenitor Inhibitory Factor 2; MPIF-2; Small-inducible Cytokine A24; CKβ6
Product Type Protein
Properties
Source/Host CHO cells
Sequence

The extracellular domain of human CCL24 (aa 27-119) is fused to the N-terminus of the Fc region of human IgG1.

Crossreactivity Human
Purity ≥98% (SDS-PAGE)
Endotoxin Content <0.06EU/μg protein (LAL test; Lonza).
Reconstitution Reconstitute 10µg vial in 100µl sterile water.
Reconstitute 50µg vial in 50µl sterile water.
Add 1X PBS to the desired protein concentration.
Formulation Lyophilized from 0.2μm-filtered solution in PBS.
Protein Negative Control

Fc (human) IgG1 Control (rec.)

Other Product Data

NCBI reference AAH69391.1: CCL24 (human)

Declaration Manufactured by Chimerigen.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

CCL24 (eotaxin-2) has been shown to induce chemotaxis of eosinophils, basophils and resting T lymphocytes but not monocytes and activated T lymphocytes. CCL24 is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated levels of CCL24 has been seen in patients with aspirin-exacerbated respiratory disease (AERD), such as asthma.

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