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Chimerigen
CCL22 (mouse):Fc (mouse) (rec.)
320
CHF
CHF 320.00
In stock
CHI-MF-110CCL22-C05050 µgCHF 320.00
| Product Details | |
|---|---|
| Synonyms | C-C Motif Chemokine 22; CC Chemokine STCP-1; Stimulated T Cell Chemotactic Protein 1; STCP1; MDC; Macrophage-derived Chemokine; Small-inducible Cytokine A22 |
| Product Type | Protein |
| Properties | |
| Source/Host | CHO cells |
| Sequence |
The extracellular domain of mouse CCL22 (aa 25-92) is fused to the N-terminus of the Fc region of mouse IgG2a. |
| Crossreactivity | Mouse |
| MW | ~35-50kDa |
| Purity | ≥98% (SDS-PAGE) |
| Endotoxin Content | <1EU/mg protein (LAL test; Lonza). |
| Reconstitution | Reconstitute at 100μg/ml in sterile PBS. |
| Formulation | Lyophilized from 0.2μm-filtered solution in PBS. |
| Protein Negative Control | |
| Other Product Data |
NCBI reference NP_033163.1: CCL22 (mouse) |
| Declaration | Manufactured by Chimerigen. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
CCL22 (C-C Motif Chemokine 22; Stimulated T cell chemotactic protein; STCP1) is a CC chemokine initially isolated from clones of monocyte-derived macrophages and binds to the receptor CCR4. Human CCL22 is highly expressed in macrophage and in monocyte-derived dendritic cells and thymus. It is also found in lymph node, appendix, activated monocytes, resting and activated macrophages. May play a role in the trafficking of activated/effector T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. CCL22 has been shown to induce chemotaxis or Ca2+ mobilization in dendritic cells, IL-2 activated NK cells and activated T lymphocytes.
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