CCL22 (mouse):Fc (mouse) (rec.)

CHF 170.00
In stock
CHI-MF-110CCL22-C01010 µgCHF 170.00
CHI-MF-110CCL22-C05050 µgCHF 300.00
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Product Details
Synonyms C-C Motif Chemokine 22; CC Chemokine STCP-1; Stimulated T Cell Chemotactic Protein 1; STCP1; MDC; Macrophage-derived Chemokine; Small-inducible Cytokine A22
Product Type Protein
Properties
Source/Host CHO cells
Sequence

The extracellular domain of mouse CCL22 (aa 25-92) is fused to the N-terminus of the Fc region of mouse IgG2a.

Crossreactivity Mouse
MW ~35-50kDa
Purity ≥98% (SDS-PAGE)
Endotoxin Content <1EU/mg protein (LAL test; Lonza).
Reconstitution Reconstitute at 100μg/ml in sterile PBS.
Formulation Lyophilized from 0.2μm-filtered solution in PBS.
Protein Negative Control

Fc (mouse) IgG2a Control (rec.)

Other Product Data

NCBI reference NP_033163.1: CCL22 (mouse)

Declaration Manufactured by Chimerigen.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

CCL22 (C-C Motif Chemokine 22; Stimulated T cell chemotactic protein; STCP1) is a CC chemokine initially isolated from clones of monocyte-derived macrophages and binds to the receptor CCR4. Human CCL22 is highly expressed in macrophage and in monocyte-derived dendritic cells and thymus. It is also found in lymph node, appendix, activated monocytes, resting and activated macrophages. May play a role in the trafficking of activated/effector T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. CCL22 has been shown to induce chemotaxis or Ca2+ mobilization in dendritic cells, IL-2 activated NK cells and activated T lymphocytes.

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