IL-22 (mouse) (recombinant protein) (His)

Specifications / Handling

More Information
Product Details
Synonyms	Interleukin-22; IL-10-related T Cell-derived-inducible Factor; ILTIF
Product Type	Protein
Properties
Source/Host	E. coli
Sequence	Mouse IL-22 (aa 34-179) is fused at the N-terminus to a His-tag.
Crossreactivity	Mouse
Purity	≥95% (SDS-PAGE)
Endotoxin Content	<1EU/μg protein (LAL test; Lonza).
Reconstitution	Reconstitute at 100μg/ml in sterile PBS.
Formulation	Lyophilized from 0.2μm-filtered solution in PBS.
Other Product Data	NCBI reference NP_058667.1: IL-22 (mouse)
Declaration	Manufactured by Chimerigen.
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Avoid freeze/thaw cycles.
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Description

Interleukin-22 (IL-22), also known as IL-10 related T cell-derived-inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal T cells upon anti-CD3 stimulation in humans. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R(CRF29) and IL-10Rβ(CRF24), belonging to the class II cytokine receptor family.

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IL-22 (mouse) (rec.) (His)