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IL-22 (mouse) (rec.) (His)
210
CHF
CHF 210.00
In stock
CHI-MR-10022-C01010 µgCHF 210.00
CHI-MR-10022-C05050 µgCHF 600.00
| Product Details | |
|---|---|
| Synonyms | Interleukin-22; IL-10-related T Cell-derived-inducible Factor; ILTIF |
| Product Type | Protein |
| Properties | |
| Source/Host | E. coli |
| Sequence | Mouse IL-22 (aa 34-179) is fused at the N-terminus to a His-tag. |
| Crossreactivity | Mouse |
| Purity | ≥95% (SDS-PAGE) |
| Endotoxin Content | <1EU/μg protein (LAL test; Lonza). |
| Reconstitution | Reconstitute at 100μg/ml in sterile PBS. |
| Formulation | Lyophilized from 0.2μm-filtered solution in PBS. |
| Other Product Data | NCBI reference NP_058667.1: IL-22 (mouse) |
| Declaration | Manufactured by Chimerigen. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Interleukin-22 (IL-22), also known as IL-10 related T cell-derived-inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal T cells upon anti-CD3 stimulation in humans. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R(CRF29) and IL-10Rβ(CRF24), belonging to the class II cytokine receptor family.
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