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RevMab
anti-alpha-Tubulin, Rabbit Monoclonal (RM113) (Biotin)
459
CHF
CHF 459.00
In stock
REV-31-1016-02-R05050 µlCHF 459.00
Figure 1: Immunocytochemical staining of HeLa cells, using Anti-α-Tubulin RevMAb Clone RM113 at 1/200 dilution (red). Nuclei have been labeled with DAPI (blue).
| Product Details | |
|---|---|
| Synonyms | Tubulin alpha-1A Chain; Tubulin alpha-1B Chain |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM113 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | A peptide corresponding to the C-terminus of α-Tubulin. |
| Label/Conjugates | Biotin |
| Application |
Western Blot (WB): 1:1000 dilution Immunoprecipitation (IP): 1:200 dilution Chromatin IP (ChIP): 1:200 dilution Immunocytochemistry (ICC): 1:200 dilution Immunohistochemistry (IHC): 1:200 dilution |
| Crossreactivity | All |
| Specificity | This antibody reacts to α-Tubulin, including Tubulin alpha-1A chain and Tubulin alpha-1B chain. |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Concentration | N/A |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | P68363 |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of α- and β-tubulin. Microtubules function as structural and mobile elements in mitosis, intracellular transport, flagellar movement, and the cytoskeleton. Two different mechanisms can generate microtubule diversity: the expression of different α- and β-tubulin genes, referred to as tubulin isotypes, and the generation of posttranslational modifications (PTMs) on α- and β-tubulin. Tubulin PTMs include the well-known acetylation or phosphorylation, and others that have so far mostly been found on tubulin, detyrosination/tyrosination, polyglutamylation and polyglycylation. These PTMs might have evolved to specifically regulate tubulin and microtubule functions.