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RevMab
IgM (human) Matched Antibody Pair
629
CHF
CHF 629.00
In stock
REV-31-1023-MK-KI011 SetCHF 629.00
Figure 1: Sandwich ELISA using RM121 as the capture antibody (100ng/well)
| Product Details | |
|---|---|
| Synonyms | Immunoglobulin M |
| Product Type | Set |
| Properties | |
| Application Set | Quantitative ELISA |
| Specificity | The antibody pair detects only human IgM. It does not react to monkey (Cyno or Rhesus) IgG, mouse IgG, rat IgG, or goat IgG. There is no cross reactivity to any other immunoglobulins or IgG subclasses. |
| Crossreactivity | Human |
| Quantity |
ELISA: Capture Antibody 50ng/well - 200ng/well Detection Antibody 0.1ug/mL - 0.5ug/mL |
| Sample Type | Serum |
| Assay Type | Sandwich |
| Kit Contains |
1) Capture Antibody: Anti-Human IgM Rabbit Monoclonal antibody, clone RM121, 100 ug at 1.0 mg/mL in 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide 2) Detection Antibody: Biotin Anti-Human Ig Light Chain Rabbit Monoclonal Antibody, Clone RM129, 25 ug at 1.0 mg/mL in 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide3) 10X Sample Diluent: Added to the tested sample to reduce non-specific background and noise |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by RevMab Biosciences. |
| Accession Number | P01871 |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| Manual | No |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
The Human IgM Matched Antibody Pairs is specific to Human IgM and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or goat immunoglobulin. The kit can be used for the detection of therapeutic antibodies from samples obtained from experimental animals to provide accurate pharmacokinetic (PK) data.
Immunoglobulin M (IgM) is one of several isotypes of antibody (also known as immunoglobulin) that are produced by vertebrates. IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. In the case of humans and other mammals that have been studied, the spleen, where plasmablasts responsible for antibody production reside, is the major site of specific IgM production.
Immunoglobulin M (IgM) is one of several isotypes of antibody (also known as immunoglobulin) that are produced by vertebrates. IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. In the case of humans and other mammals that have been studied, the spleen, where plasmablasts responsible for antibody production reside, is the major site of specific IgM production.