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RevMab
anti-IgA (mouse), Rabbit Monoclonal (RM220) (Biotin)
459
CHF
CHF 459.00
In stock
REV-31-1099-02-C05050 µgCHF 459.00
Figure 1: Western blot of nonreduced(-) and reduced(+) mouse IgA, using 0.5ug/mL of RevMAb clone RM220. This antibody reacts to nonreduced IgA.
| Product Details | |
|---|---|
| Synonyms | Immunoglobulin A |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM220 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | Mouse IgA. |
| Label/Conjugates | Biotin |
| Application |
ELISA: 0.005 µg/ml-0.2 µg/ml Immunocytochemistry (ICC): 0.5 µg/ml-2 µg/ml Immunohistochemistry (IHC): 0.5 µg/ml-2 µg/ml Western Blot (WB): 0.5 µg/ml-2 µg/ml |
| Crossreactivity | Mouse |
| Specificity | This antibody specifically reacts to mouse IgA. No cross reactivity with mouse IgG1, IgG2a, IgG2b, IgG2c, IgG3, IgM, IgE, or human IgA. |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Concentration | 1 mg/ml |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | P01878 |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Immunoglobulin A (IgA) is an antibody isotype that plays a crucial role in the immune function of mucous membranes. The IgA dimeric form is the most prevalent and is also called secretory IgA (sIgA). sIgA is the main immunoglobulin found in mucous secretions, including tears, saliva, sweat, colostrum and secretions from the genitourinary tract, gastrointestinal tract, prostate and respiratory epithelium. It is also found in small amounts in blood. The secretory component of sIgA protects the immunoglobulin from being degraded by proteolytic enzymes; thus, sIgA can survive in the harsh gastrointestinal tract environment and provide protection against microbes that multiply in body secretions. In the blood, IgA interacts with the Fc receptor called FcαRI (or CD89), which is expressed on immune effector cells, to initiate inflammatory reactions.