anti-IDH1 (R132H) (human), Rabbit Monoclonal (RM390)

CHF 426.00
In stock
REV-31-1276-00-R100100 µlCHF 426.00
More Information
Product Details
Synonyms Isocitrate Dehydrogenase 1; Oxalosuccinate Decarboxylase
Product Type Recombinant Antibody
Properties
Clone RM390
Isotype Rabbit IgG
Source/Host Rabbit
Immunogen/Antigen A peptide corresponding to human (R132H mutant specific).
Application

Immunohistochemistry (IHC): 1:100-1:200 dilution

Crossreactivity Human
Specificity

This antibody reacts to human IDH1(R132H).

Purity Protein A purified.
Purity Detail Protein A affinity purified from an animal origin-free culture supernatant.
Concentration N/A
Formulation Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Isotype Negative Control

Rabbit IgG

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Accession Number O75874
Declaration Manufactured by RevMab Biosciences.
Shipping and Handling
Shipping BLUE ICE
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Isocitrate Dehydrogenase 1 (IDH1) is a soluble, cytosolic enzyme involved in the TCA metabolic cycle. The most notable mutation in this enzyme, R132H, is clinically indicated in the majority of astrocytomas and oligodendroglial tumors, with the mutation being associated with more favourable prognosis and increased survival in those patients. IDH1 R132H is also useful in the differential diagnosis between anaplastic glioma and glioblastoma.

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