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RevMab
anti-MerTK (human), Rabbit Monoclonal (RM506)
459
CHF
CHF 459.00
In stock
REV-31-1398-00-R100100 µlCHF 459.00
Figure 1: Immunohistochemical staining of formalin-fixed and paraffin-embedded human eye retina tissue sections using anti-Human MerTK Rabbit Monoclonal Antibody (Clone RM506) at 1:100 dilution.
| Product Details | |
|---|---|
| Synonyms | Tyrosine-protein Kinase Mer; Proto-Oncogene c-Mer; Receptor Tyrosine Kinase MerTK |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM506 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | Recombinant extracellular domain of human MerTK. |
| Application |
Immunohistochemistry (IHC): 1:100-1:200 dilution |
| Crossreactivity | Human |
| Specificity |
This antibody reacts to human MerTK. |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Concentration | N/A |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | Q12866 |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
MerTK is a transmembrane receptor tyrosine kinase (RTK) that is mainly expressed in dendritic cells (DCs) and macrophages. It is a member of the TYRO3/AXL/MER (TAM) receptor kinase family, which also includes TYRO3 and AXL. MerTK plays a role in a number of important biological processes, including phagocytosis, immune regulation, angiogenesis important for wound healing and the growth of tumors and cancer. MerTK is a promising target for the development of new cancer treatments.
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