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RevMab
anti-SALL4 (human), Rabbit Monoclonal (RM522)
As low as
477
CHF
CHF 477.00
In stock
Only %1 left
REV-31-1414-00-R100100 µlCHF 477.00
NEW
Figure 1: Immunohistochemical staining of formalin fixed and paraffin embedded human testis, stained with anti-SALL4 rabbit monoclonal antibody clone RM522 at 1:100 dilution.
| Product Details | |
|---|---|
| Synonyms | Sal-like Protein 4; Zinc Finger Protein 797; ZNF797 |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM522 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | A peptide corresponding to the C-terminus of human SALL4. |
| Application |
Immunohistochemistry (IHC): 1:100-1:500 |
| Crossreactivity |
Human Mouse Rat |
| Specificity |
This antibody reacts to human SALL4 (Sal-like protein 4) protein including SALL4A and SALL4B. This antibody may also react to mouse or rat SALL4 as predicted by immunogen homology. |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| Accession Number | Q9UJQ4 |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
SALL4 (Sal-like protein 4) is a transcription factor that plays a crucial role in embryonic development, stem cell pluripotency, and cell differentiation. It is a member of the SALL gene family, characterized by zinc finger domains that enable DNA binding and gene regulation. In normal physiology, SALL4 helps maintain the self-renewal of embryonic stem cells. However, its abnormal reactivation in adult tissues has been linked to various cancers, where it contributes to tumor growth, metastasis, and resistance to therapy.