RevMab

anti-Acetylated-Lysine, Rabbit Monoclonal (RM101)

CHF 518.00
In stock
REV-32-1012-00-C100100 µgCHF 518.00
More Information
Product Details
Synonyms Kac; AcK
Product Type Recombinant Antibody
Properties
Clone RM101
Isotype Rabbit IgG
Source/Host Rabbit
Immunogen/Antigen Acetyllysine -BSA.
Application

Western Blot (WB): 1:500 -1:2000 dilution
Immunoprecipitation (IP): 1:100-1:500 dilution
Chromatin IP (ChIP): 1:100-1:500 dilution
Immunocytochemistry (ICC): 1:100-1:500 dilution
Immunohistochemistry (IHC): 1:100-1:500 dilution

Crossreactivity All
Specificity

This antibody reacts to lysine-acetylated proteins. No cross reactivity with nonacetylated lysine, and lysine with other modification.

Purity Protein A purified.
Purity Detail Protein A affinity purified from an animal origin-free culture supernatant.
Concentration 1 mg/ml
Formulation Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Isotype Negative Control

Rabbit IgG

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Accession Number N/A
Declaration Manufactured by RevMab Biosciences.
Shipping and Handling
Shipping BLUE ICE
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF
Description

Acetyllysine (or acetylated lysine) is an acetyl-derivative of the amino acid lysine. Post-translational acetylation occurs on the epsilon amino group of lysine residues as a reversible and highly dynamic post-translational modification (PTM) that is known to be a key regulator in multiple cellular events, including chromatin structure, transcription, metabolism, signal transduction and cytoskeletal regulation. The acetylation of lysine residues in proteins is an important mechanism of epigenetics. It functions by regulating the binding of histones to DNA in nucleosomes and thereby controlling the expression of genes on that DNA. Non-histone proteins are acetylated as well. Histone acetyltransferases (HATs) catalyze the addition of acetyl groups from acetyl-CoA onto certain lysine residues of histones and non-histone proteins. Histone deacetylases (HDACs) catalyze the removal of acetyl groups from acetylated lysines.

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