JNJ-7706621

CHF 150.00
In stock
SYN-1048-M0011 mgCHF 150.00
SYN-1048-M0055 mgCHF 251.00
SYN-1048-M01010 mgCHF 425.00
SYN-1048-M05050 mgCHF 999.00
SYN-1048-M100100 mgCHF 1'706.00
 
More Information
Product Details
Synonyms JNJ7706621
Product Type Chemical
Properties
Formula C15H12F2N6O3S
MW 394.4
CAS 443797-96-4
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: Aurora A - CDK7 - CDK5 - CDK4 - CDK2 | Kinase Group: Other | Substrate: Serine-Threonine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key KDKUVYLMPJIGKA-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
JNJ-7706621 is a dual inhibitor of cyclin-dependent kinases (CDK) and aurora kinases. It demonstrates highest potency on CDK1/2 with IC(50) values of 9nM and 4nM respectively. It shows more than 6-fold selectivity for CDK1/2 over CDK3/4/6.
Product References
  1. The in vitro and in vivo effects of JNJ-7706621: a dual inhibitor of cyclin-dependent kinases and aurora kinases: S. Emanuel, et al.; Cancer Res. 65, 9038 (2005)
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