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SynKinase
PIK-75
71
CHF
CHF 71.00
In stock
SYN-1067-M0011 mgCHF 71.00
SYN-1067-M0055 mgCHF 92.00
SYN-1067-M01010 mgCHF 106.00
SYN-1067-M05050 mgCHF 390.00
SYN-1067-M100100 mgCHF 546.00
| Product Details | |
|---|---|
| Synonyms | PIK75 |
| Product Type | Chemical |
| Properties | |
| Formula | C16H14BrN5O4S |
| MW | 452.3 |
| CAS | 372196-67-3 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | QTHCAAFKVUWAFI-DJKKODMXSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
PIK-75 is a PI3K inhibitor displaying selectivity for the p110α isoform (IC(50) of 6nM). PIK-75 blocks the phosphorylation of PKB induced by insulin.
Product References
- Phosphoinositide-3-kinases (PI3Ks): combined comparative modeling and 3D-QSAR to rationalize the inhibition of p110alpha: R. Frederick & W.A. Denny; J. Chem. Inf. Model 48, 629 (2008)
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