Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
SynKinase
PIK-75
71
CHF
CHF 71.00
In stock
SYN-1067-M0011 mgCHF 71.00
SYN-1067-M0055 mgCHF 92.00
SYN-1067-M01010 mgCHF 106.00
SYN-1067-M05050 mgCHF 390.00
SYN-1067-M100100 mgCHF 546.00
Product Details | |
---|---|
Synonyms | PIK75 |
Product Type | Chemical |
Properties | |
Formula | C16H14BrN5O4S |
MW | 452.3 |
CAS | 372196-67-3 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. |
Declaration | Manufactured by SynKinase. |
Other Product Data |
Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | QTHCAAFKVUWAFI-DJKKODMXSA-N |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
PIK-75 is a PI3K inhibitor displaying selectivity for the p110α isoform (IC(50) of 6nM). PIK-75 blocks the phosphorylation of PKB induced by insulin.
Product References
- Phosphoinositide-3-kinases (PI3Ks): combined comparative modeling and 3D-QSAR to rationalize the inhibition of p110alpha: R. Frederick & W.A. Denny; J. Chem. Inf. Model 48, 629 (2008)