Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
SynKinase
SD-06
As low as
CHF 0.00
In stock
Only %1 left
SYN-1078-M0011 mgCHF 270.00
SYN-1078-M0055 mgCHF 546.00
SYN-1078-M01010 mgCHF 858.00
SYN-1078-M05050 mgINQ
SYN-1078-M100100 mgINQ
| Product Details | |
|---|---|
| Synonyms | SD06 |
| Product Type | Chemical |
| Properties | |
| Formula | C20H20ClN5O2 |
| MW | 397.9 |
| CAS | 271576-80-8 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: p38 | Kinase Group: CMGC | Substrate: Serine-Threonine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | CATQHDWESBRRQA-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
SD-06 is a p38 MAP kinase inhibitor. It inhibits p38α with an IC(50) value of 170nM and inhibits LPS-stimulated TNF-release in rats.
Product References
- Pathway to the clinic: inhibition of P38 MAP kinase. A review of ten chemotypes selected for development: D.M. Goldstein & T. Gabriel; Curr. Top. Med. Chem. 5, 1017 (2005)