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SynKinase
SD-06
CHF 0.00
In stock
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| Product Details | |
|---|---|
| Synonyms | SD06 |
| Product Type | Chemical |
| Properties | |
| Formula | C20H20ClN5O2 |
| MW | 397.9 |
| CAS | 271576-80-8 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: p38 | Kinase Group: CMGC | Substrate: Serine-Threonine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | CATQHDWESBRRQA-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
SD-06 is a p38 MAP kinase inhibitor. It inhibits p38α with an IC(50) value of 170nM and inhibits LPS-stimulated TNF-release in rats.
Product References
- Pathway to the clinic: inhibition of P38 MAP kinase. A review of ten chemotypes selected for development: D.M. Goldstein & T. Gabriel; Curr. Top. Med. Chem. 5, 1017 (2005)