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Vandetanib
72
CHF
CHF 72.00
In stock
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SYN-1090-M100100 mgCHF 467.00

Product Details | |
---|---|
Synonyms | ZD6474; Zactima; Vandetanib |
Product Type | Chemical |
Properties | |
Formula | C22H24BrFN4O2 |
MW | 475.4 |
CAS | 443913-73-3 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO or ethanol. |
Declaration | Manufactured by SynKinase. |
Other Product Data |
Target: EGFR - HER2 | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | UHTHHESEBZOYNR-UHFFFAOYSA-N |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS |
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Product Specification Sheet | |
Datasheet |
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Vandetanib is a tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor (VEGFR, IC(50) of 40nM) and the epidermal growth factor receptor (EGFR).
Product References
- ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases: F. Carlomagno, et al.; Cancer Res. 62, 7284 (2002)